Medications
How the drug abemaciclib treats breast cancer
The anti-cancer drug abemaciclib (also known as Vernezio) has been added to the Australian Pharmaceutical Benefits Scheme (PBS) to treat certain types of breast cancer.
5 hours ago
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News tagged with blood brain barrier
Medical research
Research on how dietary choline travels through the blood-brain barrier reveals pathway for treating brain disorders
A University of Queensland researcher has found molecular doorways that could be used to help deliver drugs into the brain to treat neurological disorders.
May 1, 2024
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Medications
Targeting specific protein regions offers a new treatment approach in medulloblastoma
Medulloblastoma (the most common malignant childhood brain tumor) is separated into four molecular groups, with Group 3 bearing the worst prognosis. By studying EP300 and CBP, critical proteins in Group 3 medulloblastoma ...
Apr 25, 2024
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Immunology
Swimming short fibrous nasal drops achieve intraventricular administration
Adequate drug delivery across the blood-brain barrier is a critical factor in treating central nervous system (CNS) disorders. Inspired by swimming fish and the microstructure of the nasal cavity, Prof. Cui is the first to ...
Apr 23, 2024
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Genetics
New gene therapy for metachromatic leukodystrophy proves effective in mice
Metachromatic leukodystrophy is a rare genetic disorder that mainly affects young children and results in severe neurological symptoms accompanied by a loss of motor and intellectual capacities. At Paris Brain Institute, ...
Apr 22, 2024
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Neuroscience
A new therapeutic target for traumatic brain injury
For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely. Not only can these injuries lead to a loss of coordination, depression, impulsivity, and difficulty concentrating, ...
Apr 19, 2024
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Medical research
Battle against fatal neurodegenerative disease advances on two fronts
European researchers are pioneering a vaccine and treatment for amyotrophic lateral sclerosis.
Apr 19, 2024
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Alzheimer's disease & dementia
Obesity-induced cognitive decline: Role of brain oxidation and tocotrienols
Obesity has become a pressing worldwide health issue, with rates steadily rising over recent decades. Beyond its well-documented associations with physical health issues, such as cardiovascular disease and diabetes, obesity ...
Apr 18, 2024
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Genetics
Newly found genetic variant defends against Alzheimer's disease
Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease. The study, "Rare ...
Apr 10, 2024
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Medications
AZD1390 with radiotherapy shows manageable safety profile and preliminary efficacy for patients with glioblastoma
AZD1390, an ataxia telangiectasia mutant (ATM) kinase inhibitor, demonstrated a manageable safety profile in both recurrent and newly diagnosed glioblastoma (GBM) patients when given in combination with standard-of-care radiotherapy ...
Apr 9, 2024
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