(Antibody) orientation matters
The orientation of antibody binding to bacteria can mean life or death to the bug, according to a study published in The Journal of Experimental Medicine on December 10th. These findings may help explain why these bacter ...
Medical research
Dec 10, 2012 |
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Combination therapy using JAK2 and HSP90 inhibitors increased efficacy in myelofibrosis in vivo
Researchers have demonstrated that combination therapy with PU-H71 and ruxolitinib increases the durability and effectiveness of a treatment that had previously shown limited utility for patients with myelofibrosis.
Cancer
Dec 09, 2012 |
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Study finds protein in platelets fight malaria but only for some people
(Medical Xpress)—Researchers in Australia have found that a protein in platelets found naturally in blood has a protective effect against malaria. In their paper published in the journal Science, the team describes how th ...
Medical research
Dec 07, 2012 |
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Mouse study offers clues to obesity-diabetes link
(HealthDay)—Obesity and type 2 diabetes are clearly intertwined, but researchers say they've found a way to weaken the connection between the two—at least in mice.
Medical research
Dec 06, 2012 |
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Study identifies 75 genetic regions that influence red blood cell formation
New research is revealing how red blood cells are made and how the body regulates the amount of haemoglobin that is packaged in red blood cells at any time. Genomic analysis techniques have doubled the number of genetic regions ...
Genetics
Dec 05, 2012 |
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Breast cancer drug could hold the key to fighting other tumours
New research out of the United Kingdom is showing that a common drug used in the fight against breast cancer could also be employed in the fight against other tumours. The drug in question is geldanamycin, ...
Cancer
Dec 05, 2012 |
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Novel antibodies for combating Alzheimer's and Parkinson's disease
Antibodies developed by researchers at Rensselaer Polytechnic Institute are unusually effective at preventing the formation of toxic protein particles linked to Alzheimer's disease and Parkinson's disease, ...
Neuroscience
Dec 03, 2012 |
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Neuroblastoma patients with ARID1A and ARID1B mutations have more aggressive disease
In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia (CHOP) found that patients with changes in two genes, ARID1A ...
Genetics
Dec 02, 2012 |
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Cometriq approved for rare thyroid cancer
(HealthDay)—Cometriq (cabozantinib) has been approved by the U.S. Food and Drug Administration to treat modullary thyroid cancer that has spread to other parts of the body, the agency said Thursday.
Medications
Nov 29, 2012 |
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Double duty: Immune system regulator found to protect brain from effects of stroke
A small molecule known to regulate white blood cells has a surprising second role in protecting brain cells from the deleterious effects of stroke, Johns Hopkins researchers report. The molecule, microRNA-223, affects how ...
Immunology
Nov 28, 2012 |
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Alzheimer's disease in mice alleviated promising therapeutic approach for humans
Pathological changes typical of Alzheimer's disease were significantly reduced in mice by blockade of an immune system transmitter. A research team from Charité - Universitätsmedizin Berlin and the University ...
Alzheimer's disease & dementia
Nov 25, 2012 |
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Arginine and proline enriched diet may speed wound healing in diabetes
Chronic wounds such as foot ulcers are a common problem for diabetics and are the cause of more than 80 percent of the lower leg amputations in these patients. There is currently no effective way to improve healing of these ...
Diabetes
Nov 15, 2012 |
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Discovery could lead to faster diagnosis for some chronic fatigue syndrome cases
For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome (CFS), a complex disorder with no known definitive cause or cure.
Diseases, Conditions, Syndromes
Nov 14, 2012 |
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G proteins regulate remodelling of blood vessels
Blood vessels are extremely dynamic: depending on the external conditions, they can adapt their permeability for nutrients, their contractility, and even their shape. Unlike cardiac muscle cells, for example, ...
Medical research
Nov 13, 2012 |
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Scientists discover how stomach cancer spreads
Scientists at the University of Liverpool have found that the production of a protein that prevents the growth and spread of cancerous cells is impaired in patients with gastric cancer.
Cancer
Nov 13, 2012 |
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