Bone marrow transplant arrests symptoms in model of Rett syndrome
A paper published online today in Nature describes the results of using bone marrow transplant (BMT) to replace faulty immune system cells in models of Rett Syndrome. The procedure arrested many severe sympto ...
Immunology
Mar 18, 2012 |
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Combination treatment in mice shows promise for fatal neurological disorder in kids
Infants with Batten disease, a rare but fatal neurological disorder, appear healthy at birth. But within a few short years, the illness takes a heavy toll, leaving children blind, speechless and paralyzed. ...
Neuroscience
Mar 15, 2012 |
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Genetic profiling helps doctors more accurately predict prognosis, guide treatment decisions for leukemia patients
Researchers have identified a set of genetic abnormalities in patients with acute myelogenous leukemia (AML) that doctors can use to more accurately predict patients' prognoses and select treatments that are most likely to ...
Cancer
Mar 14, 2012 |
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Scientists isolate egg-producing stem cells from adult human ovaries
For the first time, Massachusetts General Hospital (MGH) researchers have isolated egg-producing stem cells from the ovaries of reproductive age women and shown these cells can produce what appear to be normal egg cells or ...
Medical research
Feb 26, 2012 |
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Complications of blood cancers make termination advisable at early stages of pregnancy
Lymphoma is the fourth most common cancer in pregnancy, affecting one in 6000 pregnancies. Non-Hodgkin lymphoma, acute leukaemia, and other blood cancers, while also rare, can also occur in pregnancy. The need for urgent ...
Obstetrics & gynaecology
Feb 09, 2012 |
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Survival rates for pediatric bone marrow transplants top in nation
The UCSF Benioff Children's Hospital has the best overall survival rates in the nation for bone marrow transplants, according to a recent independent review of 156 programs nationwide.
Other
Jan 26, 2012 |
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Ontario's first cardiac stem cell transplant performed last week
Heart failure is a leading cause of death in Canada. As part of the ongoing IMPACT-CABG clinical trial to treat advanced heart failure, physicians at the Peter Munk Cardiac Centre performed the first cardiac stem cell transplant ...
Cardiology
Jan 26, 2012 |
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Natural enzyme provides potential new approach for treating graft-vs-host disease
A natural enzyme derived from human blood plasma showed potential in significantly reducing the effects of graft-vs.-host disease, a common and deadly side effect of lifesaving bone marrow transplants.
Medical research
Jan 17, 2012 |
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University of Kentucky offers stroke stem cell trial
The University of Kentucky will be the first site in the state and one of a select few in the entire country participating in the first stages of a groundbreaking study to investigate the effects of MultiStem, a human adult ...
Medical research
Jan 13, 2012 |
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Towards more effective treatment for multiple myeloma
A new study from SUNY Downstate Medical Center in Brooklyn, New York, shows that MAL3-101, a recently developed inhibitor of the heat shock protein 70 (Hsp70), appears to have potent anti-tumor effects on multiple myeloma, ...
Cancer
Jan 09, 2012 |
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Bone marrow-derived cells differentiate in the brain through mechanisms of plasticity
Bone marrow-derived stem cells (BMDCs) have been recognized as a source for transplantation because they can contribute to different cell populations in a variety of organs under both normal and pathological conditions. Many ...
Medical research
Dec 19, 2011 |
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Study of two sisters sheds light on lymphoma evolution
When a 41-year-old woman was diagnosed with chronic-phase chronic myeloid leukemia, she received a bone marrow transplant and subsequent leukocyte infusion from her sister. These treatments controlled her leukemia, but seven ...
Cancer
Dec 12, 2011 |
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Bone marrow and blood stem cell transplant survival rates equal, when donor is unrelated to patient
Patients who receive a blood stem cell transplant from a donor outside of their family to treat leukemia and other blood diseases are more likely to have graft failure but less likely to experience graft-versus-host disease, ...
Medical research
Dec 12, 2011 |
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Researchers identify agent responsible for protection against early stages of atherosclerosis
Researchers from Boston University School of Medicine (BUSM) have identified for the first time the A2b adenosine receptor (A2bAR) as a possible new therapeutic target against atherosclerosis resulting from a diet high in ...
Cardiology
Dec 12, 2011 |
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Ruxolinitib better at reducing myelofibrosis symptoms, study shows
In a major advance in treatment, a multicenter study found that ruxolinitib did a better job than off-label chemotherapy drugs reducing the terrible symptoms associated with myelofibrosis, including pain, enlarged spleen, anemia, fever, chills ...
Cancer
Dec 12, 2011 |
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