Medical research

Inflammation is associated with bone growth

Researchers use induced pluripotent stem cells in a mouse model to show that diseased bone growth may be stimulated by a key molecule for inflammation. Inhibition of activin-A was found to repress the bone overgrowth typically ...

Oncology & Cancer

Microenvironment provides growth factor for metastasis

Healthy bone is continuously involved in a dynamic process that includes bone deposition and bone resorption. However, when a person has cancer that spreads to the bone and bone marrow, the tissue becomes increasingly fragile, ...

Oncology & Cancer

Fruit flies reveal features of human intestinal cancer

Researchers in Spain have determined how a transcription factor known as Mirror regulates tumour-like growth in the intestines of fruit flies. The scientists believe a related system may be at work in humans during the progression ...

Oncology & Cancer

Researchers explore function of cancer-causing gene

Developmental biologists at the University of Georgia are discovering new roles for a specific gene known as Max's Giant Associated protein, or MGA. A little studied protein, MGA appears to control a number of developmental ...

Medical research

New genetic cause of pulmonary hypertension identified

Columbia University Medical Center (CUMC) scientists have identified new genetic mutations that can cause pulmonary arterial hypertension (PAH), a rare fatal disease characterized by high blood pressure in the lungs. The ...

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