Neuroscience

Fine tuning first-responder immune cells may reduce TBI damage

Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report.

Neuroscience

Timing is of the essence when treating brain swelling in mice

Researchers from the National Institutes of Health have discovered Jekyll and Hyde immune cells in the brain that ultimately help with brain repair but early after injury can lead to fatal swelling, suggesting that timing ...

Neuroscience

Cannabinoids may help limit secondary damage of TBIs

In the hours and days after a traumatic brain injury, inflammation inside the brain can accelerate to the point that more brain damage occurs, says a scientist working to better understand the acceleration and whether interventions ...

Diabetes

Novel therapy approach for hyperinsulinemic hypoglycemia

A new method to treat hyperinsulinemic hypoglycemia has proven highly selective in targeting lesions and effective in slowing tumor growth, according to research published in the November issue of the Journal of Nuclear Medicine. ...

Immunology

Why protecting the brain against infection takes guts

The brain is uniquely protected against invading bacteria and viruses, but its defence mechanism has long remained a mystery. Now, a study in mice, confirmed in human samples, has shown that the brain has a surprising ally ...

Neuroscience

Microglia might lessen seizure severity in epilepsy

New research in mice highlights the potential protective effect of microglia—a type of non-neuronal cell in the brain—against overactivation of the central nervous system during acute epileptic seizures. The study is ...

Neuroscience

Probe detects the destruction of defective mitochondria

A versatile probe that can detect with pinpoint accuracy the programmed destruction of defective mitochondria—the powerhouses of cells—has been developed by RIKEN researchers. They used it to show that damaged mitochondria ...

Neuroscience

Tiny molecule could protect newborns from brain damage

Oxygen deprivation can be the worst start to a newborn's life, resulting in brain damage, epilepsy, developmental delays and death. It affects millions of babies around the world each year, either through pregnancy and delivery ...

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