Oncology & Cancer

New drug targets for BRCA-driven cancer uncovered

BRCA1 and BRCA2 ("BReast CAncer genes") are critical tumor suppressor genes—women carrying a mutation in one of these genes have up to an 80 percent risk of developing breast cancer and a 50 percent risk of developing ovarian ...

Oncology & Cancer

Breast cancer drugs could help treat resistant lung cancers

A class of drugs used to treat certain breast cancers could help to tackle lung cancers that have become resistant to targeted therapies, suggests a new study in mice from the Francis Crick Institute and the Institute of ...

Oncology & Cancer

A novel molecule could spur new class of drugs for breast cancer

Researchers at Stevens Institute of Technology and colleagues have designed and developed a new class of molecules that use a never-before-known mechanism that may halt or destroy breast cancer tumors, particularly for patients ...

Oncology & Cancer

'Embattled' breast cancer drugs could be revived by new discovery

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells—known as the PI3 kinase (PI3K) pathway—but efforts to develop therapies targeting this pathway have ...

Oncology & Cancer

Scientists discover how breast cancer hibernates: study

Scientists have identified the mechanism that allows breast cancer cells to lie dormant in other parts of the body only to reemerge years later with lethal force, according to a study published Tuesday.

Oncology & Cancer

Targeted 'click-to-release' chemotherapy gives good results in mice

Tagworks Pharmaceuticals, based at Radboud University Medical Center, has developed a new technique for the targeted delivery of chemotherapy for tumors in difficult cases. By way of controlled 'click-to-release' of the chemotherapy ...

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