A new University of Colorado Boulder-led study sheds light on a protein key to controlling how cells grow, proliferate and function and long implicated in tumor development.
Nov 4, 2020
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Within the first 5 years after the birth of a child, women are at an increased risk of developing metastatic breast cancer. Women diagnosed with postpartum breast cancer have a decreased disease free survival time compared ...
Sep 24, 2014
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Many diseases caused by a dysregulated immune system, such as allergies, asthma and autoimmunity, can be traced back to events in the first few months after birth. To date, the mechanisms behind the development of the immune ...
Jun 17, 2021
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First Nations, Métis and Inuit people with primary biliary cholangitis—a debilitating autoimmune liver disease—have more advanced symptoms at diagnosis and worse long-term outcomes than others in Canada, according to ...
Feb 3, 2023
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Breast cancer cells became resistant to therapeutics targeting CDK4/6, such as palbociclib (Ibrance), in multiple ways, and preclinical studies suggested different combinations of therapeutics may prevent and overcome the ...
Mar 28, 2016
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Treating women with early stage breast cancer with a combination of chemotherapy and the molecularly targeted drug Herceptin significantly increases survival in patients with a specific genetic mutation that results in very ...
Oct 5, 2011
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Despite the overall success of hormone therapy, breast cancer tumors in patients with metastatic disease often fail to respond. One new mechanism that can explain resistance to hormone therapy in breast cancer involves two ...
Oct 4, 2016
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An immunotherapy drug called pembrolizumab has been shown to significantly reduce disease recurrence in patients with the most aggressive type of breast cancer, according to results from a phase III clinical trial led by ...
Feb 10, 2022
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A new editorial paper, titled "The senescence-associated secretory phenotype induces neuroendocrine transdifferentiation," was recently published in the journal Aging
May 12, 2023
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Long-term use of high-dose green tea extract may provide some protection against cancer, cardiovascular disease, obesity and type 2 diabetes, but it also may create liver damage in a small minority of the population.
Dec 1, 2022
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