Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...
Cancer
May 06, 2013 |
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How some cancers 'poison the soil' to block metastasis
Cancer spread or metastasis can strike unprecedented fear in the minds of cancer patients. The "seed and the soil" hypothesis proposed by Stephen Paget in 1889 is now widely accepted to explain how cancer cells (seeds) are ...
Cancer
Apr 30, 2013 |
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Battery of tests on cancer cells shows them as 'squishy,' yet tactically strong
A team of student researchers and their professors from 20 laboratories around the country have gotten a new view of cancer cells. The work could shed light on the transforming physical properties of these cells as they metastasize, ...
Cancer
Apr 26, 2013 |
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Inhibiting enzymes in the cell may lead to development and proliferation of cancer cells
Blocking certain enzymes in the cell may prevent cancer cell division and growth, according to new findings from researchers at the Graduate School of Biomedical Sciences at the Icahn School of Medicine at Mount Sinai. The ...
Cancer
Apr 25, 2013 |
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Using genetic variants to improve PSA testing technique and reduce biopsies
With the help of genetics, prostate specific antigen (PSA) screenings may become more accurate and reduce the number of unnecessary prostate biopsies, according to a new study from Northwestern Medicine.
Cancer
Apr 24, 2013 |
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Dietary medium chain triglycerides prevent nonalcoholic fatty liver disease
Scientists at the Arkansas Children's Nutrition Center, a U.S. Department of Agriculture Agricultural Research Service Human Nutrition Research Center at the University of Arkansas for Medical Sciences, led by Dr. Martin ...
Diseases, Conditions, Syndromes
Apr 24, 2013 |
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Researchers discover link between inherited endocrine tumor syndrome and well-studied cell pathway
(Medical Xpress)—A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1). Individuals with MEN1 are at a substantially increased risk of ...
Cancer
Apr 24, 2013 |
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Computer program identifies rare mutations harbored within diverse populations of cancer cells and microorganisms
A tumor is not a uniform mass of identical cells. However, teasing apart genetic heterogeneity within a biopsied tumor can be difficult. Researchers often fail to tell the difference between a rare variant ...
Cancer
Apr 24, 2013 |
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Vitamin E identified as potential weapon against obesity
A potential new way to fight obesity-related illness has been uncovered, thanks to serendipitous research led by investigators at the Case Western Reserve University School of Medicine.
Overweight and Obesity
Apr 23, 2013 |
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Drug reduces fat by blocking blood vessels
Researchers have long known that cancerous tumors grow collections of abnormal blood cells, the fuel that feeds this disease and keeps it growing. Now, new evidence in an animal model suggests that blood vessels in the fat ...
Medical research
Apr 23, 2013 |
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Research shows oral supplement increases body's storage of antioxidant
(Medical Xpress)—Oral supplementation of glutathione is effective in increasing the body's stores of the antioxidant, said Penn State College of Medicine researchers in study results presented at a conference today (April ...
Medical research
Apr 23, 2013 |
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A different view of cancer cells: New study measures physical changes in tumor cells as they become metastatic
Most cancer deaths are caused by metastatic tumors, which break free from the original cancer site and spread throughout the body. For that to happen, cancer cells must undergo many genetic and physical changes.
Cancer
Apr 23, 2013 |
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Deficiency in p53 anti-tumor protein delays DNA repair after radiation
Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...
Cancer
Apr 23, 2013 |
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Metastasis stem cells in the blood of breast cancer patients discovered
Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the ...
Cancer
Apr 22, 2013 |
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Cancer drugs taking shape
In the era of molecular medicine, potentially active compounds for use in cancer therapies can be identified faster than ever before. Yet pinpointing the molecular target of an anticancer compound and deducing ...
Cancer
Apr 22, 2013 |
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