News tagged with cancer biomarkers


Genetic test helps predict risk of prostate cancer recurrence

(Medical Xpress)—Prostate cancer ranks as the most common internal malignancy diagnosed in men in the United States, but often does not require extensive treatment.

Cancer created May 10, 2013 | popularity not rated yet | comments 0

Certain bladder-cancer patients may be at high risk of disease recurrence despite bladder removal

Patients with advanced bladder cancers that are surgically removed might need additional therapy to prevent recurrence in certain situations, a new UT Southwestern Medical Center study suggests.

Cancer created May 07, 2013 | popularity not rated yet | comments 0

Team finds markers related to ovarian cancer survival and recurrence

(Medical Xpress)—Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with ...

Cancer created Apr 30, 2013 | popularity not rated yet | comments 1 | with audio podcast

Multicenter study confirms low testosterone in 84 percent of lung cancer patients taking crizotinib

A previous study by the University of Colorado Cancer Center reported the common side effect of low testosterone in men treated with the recently approved lung cancer agent, crizotinib. A new study published this week in ...

Cancer created Apr 16, 2013 | popularity 5 / 5 (3) | comments 0

Cohort study indicates that selenium may be protective against advanced prostate cancer

A greater level of toenail selenium was associated with a significant decrease in the risk for advanced prostate cancer, according to data presented at the AACR Annual Meeting 2013, held in Washington, D.C., April 6-10.

Cancer created Apr 10, 2013 | popularity not rated yet | comments 0

Genetic biomarker may help identify neuroblastomas vulnerable to novel class of drugs

An irregularity within many neuroblastoma cells may indicate whether a neuroblastoma tumor, a difficult-to-treat, early childhood cancer, is vulnerable to a new class of anti-cancer drugs known as BET bromodomain inhibitors, ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Possible predictive biomarker for patients who may respond to autophagy inhibitors

Autophagy, the process by which cells that are starved for food resort to chewing up their own damaged proteins and membranes and recycling them into fuel, has emerged as a key pathway that cancer cells use to survive in ...

Cancer created Apr 08, 2013 | popularity not rated yet | comments 0

Biomarkers discovered that may help predict response to drugs targeting KRAS-mutated NSCLC

Scientists have identified biomarkers that may help predict whether patients with KRAS-mutated non-small cell lung cancer (NSCLC) will respond to concurrent treatment with an MEK inhibitor and a PI3 kinase inhibitor, a drug ...

Cancer created Apr 08, 2013 | popularity not rated yet | comments 0

Cisplatin-resistant cancer cells sensitive to experimental anticancer drugs, PARP inhibitors

Poly (ADP-ribose) polymerase inhibitors may be a novel treatment strategy for patients with cancer that has become resistant to the commonly used chemotherapy drug cisplatin, according to data from a preclinical study published ...

Cancer created Apr 03, 2013 | popularity 5 / 5 (1) | comments 0

Scientists find promising new target for aggressive breast cancer

Women with triple-negative breast cancer are more likely to have high levels of the MET biomarker in their tumours, making it a good new target for cancer drugs according to research published in the British Jo ...

Cancer created Mar 20, 2013 | popularity not rated yet | comments 0

How some prostate tumors resist treatment—and how it might be fixed

Hormonal therapies can help control advanced prostate cancer for a time. However, for most men, at some point their prostate cancer eventually stops responding to further hormonal treatment. This stage of ...

Cancer created Mar 18, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Epigenetic changes play a key role in development of chemo resistance in BCa

At the 28th Annual EAU Congress currently ongoing in Milan until Tuesday, W. Tan and colleagues presented their study on neoadjuvant cisplatin-based chemotherapy which showed that epigenetic changes are potential key drivers ...

Cancer created Mar 18, 2013 | popularity not rated yet | comments 0

Trio of biomarkers may help identify kidney cancer in early stages

A new immunoassay that tests for the presence of three biomarkers appears to be a valid screening method for the early detection of malignant kidney cancer, according to data published in Cancer Epidemiology, Biomarkers & ...

Cancer created Mar 11, 2013 | popularity not rated yet | comments 0

Tumors deliberately create conditions that inhibit body's best immune response

New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune respon ...

Cancer created Mar 01, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Obesity, physical inactivity linked with risk for certain molecular subtype of colorectal cancer

An increasing body mass index was associated with a higher risk for colorectal cancer with a specific molecular characteristic, and inversely, physical activity was linked to a decreased risk for that same cancer, according ...

Cancer created Feb 26, 2013 | popularity 5 / 5 (1) | comments 0