A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led by the University of ...
Mar 26, 2019
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37
Some 15 to 20 percent of all breast cancers are triple-negative, meaning they lack receptors for estrogen, progesterone and human epidermal growth factor type 2. They have the worst prognosis of all breast cancers and very ...
Mar 20, 2019
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25
Ovarian cancer is not the most common form of cancer, but it's among the deadliest. That's because about 70 percent of cases recur. A new study by researchers at the University of Pittsburgh, UPMC Hillman Cancer Center, Magee-Womens ...
Mar 12, 2019
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605
NUS chemists have developed a novel ratiometric fluorescent probe for studying cellular activity of the clinically important anticancer drug cisplatin for next generation drug development.
Feb 19, 2019
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6
Researchers from the University of Alberta may have found a way to make chemotherapy more effective at treating cancer while blocking its harmful side-effects on the heart.
Feb 6, 2019
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125
An international team of researchers reports that modifying an adenovirus a certain way made it an effective tumor killer in mice with retinoblastoma. In their paper published in the journal Science Translational Medicine, ...
Some patients with breast cancer receive chemotherapy before the tumor is removed with surgery. This approach, called neoadjuvant therapy, helps to reduce the size of the tumor to facilitate breast-conserving surgery, and ...
Jan 2, 2019
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482
Due to their powerful tumour-killing effect, metal-based chemotherapies are frequently used in cancer treatment. However, it was hitherto assumed that they damaged the immune system, because of their cytotoxic (cell-damaging) ...
Dec 18, 2018
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25
More than half of cancer survivors suffer from cognitive impairment from chemotherapy that lingers for months or years after the cancer is gone. In a new study explaining the cellular mechanisms behind this condition, scientists ...
Dec 6, 2018
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2070
The selection of a first-line chemotherapy drug to treat many types of cancer is often a clear-cut decision governed by standard-of-care protocols, but what drug should be used next if the first one fails?
Nov 7, 2018
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90
