Study identifies possible new acute leukemia marker, treatment target
A study has identified microRNA-155 as a new independent prognostic marker and treatment target in patients with acute myeloid leukemia that has normal-looking chromosomes under the microscope (that is, cytogenetically normal ...
Cancer
May 13, 2013 |
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Gene mutation as cause of breast and ovarian cancer
A change to the so-called TERT gene considerably increases the risk of breast and ovarian cancer. This is the result of a current, multicenter study in which the University Department of Gynaecology and the ...
Cancer
May 10, 2013 |
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Research reveals cancer-suppressing protein 'multitasks'
The understanding of how a powerful protein called p53 protects against cancer development has been upended by a discovery by Walter and Eliza Hall Institute researchers.
Cancer
May 09, 2013 |
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Your immune system: On surveillance in the war against cancer
Predicting outcomes for cancer patients based on tumor-immune system interactions is an emerging clinical approach, and new research from Wake Forest Baptist Medical Center is advancing the field when it comes to the most ...
Genetics
May 09, 2013 |
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Red hair pigment might raise melanoma risk, study says
(HealthDay)—The red in redheads' hair is thought to put them at increased risk of the dangerous skin cancer melanoma, even if they don't spend a lot of time in the sun, according to a new study.
Cancer
May 09, 2013 |
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New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice
(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...
Cancer
May 08, 2013 |
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Researchers discover possible trigger for spread of head and neck cancer cells
(Medical Xpress)—Very little has been known about the epigenetic events—developmental and environmental factors affecting genes—that occur prior to the invasive growth of head and neck squamous cell carcinomas and their ...
Cancer
May 08, 2013 |
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Gene test may help guide prostate cancer treatment
A new genetic test to gauge the aggressiveness of prostate cancer may help tens of thousands of men each year decide whether they need to treat their cancer right away or can safely monitor it.
Genetics
May 08, 2013 |
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Amplification of a Stat5 gene produces excess oncogenic protein that drives prostate cancer spread
An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells ...
Cancer
May 07, 2013 |
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Genetic variations associated with susceptibility to bacteria linked to stomach disorders
Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and st ...
Diseases, Conditions, Syndromes
May 07, 2013 |
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MicroRNA cooperation mutes breast cancer oncogenes
A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot ...
Cancer
May 07, 2013 |
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Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...
Cancer
May 06, 2013 |
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Activity of cancer inducing genes can be controlled by the cell's skeleton
Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis. ...
Cancer
May 06, 2013 |
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Study opens new prospects for developing new targeted therapies for breast cancer
A study led by prominent breast cancer experts from Europe and the US has revealed a number of potentially important prospects for targeted therapies, and brings opportunities of truly personalised therapy for breast cancer ...
Cancer
May 02, 2013 |
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Study reveals magnitude of variation in gene expression measurements within breast cancers
An important new study has revealed the clearest picture yet of precisely how much measurement variation influences gene expression profiles of breast cancer.
Cancer
May 02, 2013 |
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