Tumor DNA is cluttered with genomic alterations, the vast majority of which have little or no functional or clinical relevance. This means that even when cancer researchers discover an alteration in a tumor or a line of cancer ...
Jun 29, 2016
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A team of scientists has developed a computational method to map cancer progression, an advance that offers new insights into the factors that spur this affliction as well as new ways of selecting effective therapies.
Jun 27, 2016
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Little is known about the molecular basis of aberrant protein glycosylation, a complex enzymatic process that is a hallmark of many human cancers including colorectal cancers (CRC), and how it may contribute to tumor progression. ...
Apr 4, 2016
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Researchers have discovered that eliminating cells thought to aid tumor growth did not slow or halt the growth of cancer tumors. In fact, when the cancer-associated fibroblasts (CAFs), were eliminated after 10 days, the risk ...
Feb 19, 2016
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In cancer, cell signaling pathways are the critical chain of events that can either quash or quicken disease progression.
Jan 11, 2016
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Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have delineated novel molecular interactions affecting the activity of the TGF-β pathway, a key cancer ...
Dec 21, 2015
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Scientists know that activation of growth factor receptors like epidermal growth factor receptors (EGFR) promote tumor progression in many types of cancer.
Aug 17, 2015
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Researchers at the University of Pittsburgh School of Medicine have identified two new classes of RNAs that are closely associated with a protein known to be a prognostic biomarker for breast cancer and could play a role ...
May 26, 2015
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A new study led by researchers at Sweden's Karolinska Institutet and Nanyang Technological University in Singapore, provides experimental evidence that a drug that inhibits the EphB-signaling pathway in the cell effectively ...
Apr 1, 2015
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Moffitt Cancer Center researchers are using integrative approaches to study cancer by combining mathematical and computational modeling with experimental and clinical data. The use of integrative approaches enables scientists ...
Mar 27, 2015
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