Oncology & Cancer

Immune cell receptor provides promising immunotherapy target

Drugs that target a receptor on immune cells called activin receptor 1C may combat tumor-induced immune suppression and help patients' immune systems fight back against cancer, according to a study by investigators at the ...

Oncology & Cancer

Researchers reveal mechanism of drug reactivating tumor suppressors

Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes. They also demonstrated ...

Oncology & Cancer

Hitchhiking cancer vaccine makes progress in the clinic

Therapeutic cancer vaccines are an appealing strategy for treating malignancies. In theory, when a patient is injected with peptide antigens—protein fragments from mutant proteins only expressed by tumor cells—T cells ...

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