Oncology & Cancer

Researchers identify protein that controls CAR T cell longevity

CAR T cell therapy has revolutionized the way certain types of cancer are treated, and the longer those CAR T cells live in a patient's body, the more effectively they respond to cancer. Now, in a new study, researchers at ...

Oncology & Cancer

Characterization of mutational 'coldspots' in the cancer genome

Mutations are the changes in the DNA that gradually occur in human cells as they replicate, and the organism grows and ages. Some of these changes, particularly when they occur in genes, can be instrumental during the development ...

Oncology & Cancer

Novel mechanism supports antitumor response and T-cell survival

A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of ...

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