The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows. In order to safeguard healthy and functioning ...
Nov 26, 2019
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Cancer cells are characterised by the ability to evade apoptosis, a type of programmed cell death that allows the organism to remove damaged cells. Many studies devoted to new chemotherapy treatments aim to induce apoptosis ...
Apr 17, 2019
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Cell death is an important aspect of tissue homeostasis, as well as inflammation and disease pathogenesis related to infection, injury, and tumor growth. Tumor necrosis factor-α (TNFα) coordinates cell death in a variety ...
Jan 17, 2019
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A highly detailed study of how the roundworm C. elegans forms oocytes suggests that the egg-making process leads to the formation and subsequent destruction of cells with an extra nucleus, but that some cellular materials ...
Jul 19, 2018
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Structural biologists at St. Jude Children's Research Hospital have discovered how a key protein functions to trigger cell's suicide machinery, called apoptosis. The scientists found that the protein, called BOK, is controlled ...
May 17, 2018
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Despite many successes in treating pediatric cancer, young children remain at high risk for developing severe, long-lasting impairments in their brain, heart, and other vital organs from chemotherapy and radiation treatments. ...
Dec 22, 2016
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Billions of cells in our bodies die every day in an important process called apoptosis. Now, researchers at the RIKEN Brain Science Institute have mapped out a sequence of events that are necessary for apoptosis to occur ...
Dec 20, 2016
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New research from the University of Liverpool has identified the role of a specific protein in the human body that can help prevent the survival and spread of eye cancer, by initiating cancer 'cell-suicide'.
Dec 6, 2016
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Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer in Switzerland. Despite intensive chemotherapy, one fifth of the patients suffer a relapse, which usually goes hand in hand with a poor prognosis. ...
May 18, 2016
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You've probably never heard of 'sphingolipids' before. But these curiously named organic compounds play a vital role in one of humanity's most well-known diseases: cancer.
Dec 17, 2015
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