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News tagged with cell death

New immune system discovered

(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.

Immunology created May 20, 2013 | popularity 4.8 / 5 (26) | comments 8 | with audio podcast

Study details genes that control whether tumors adapt or die when faced with p53 activating drugs

When turned on, the gene p53 turns off cancer. However, when existing drugs boost p53, only a few tumors die – the rest resist the challenge. A study published in the journal Cell Reports shows how: tumors that live even i ...

Cancer created May 22, 2013 | popularity not rated yet | comments 0 | with audio podcast

Scientists identify molecular trigger for Alzheimer's disease

Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease – when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons ...

Alzheimer's disease & dementia created May 20, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Study IDs key protein for cell death, offers way to kill cancer cells by forcing them into programmed-death pathway

When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ...

Genetics created May 14, 2013 | popularity 5 / 5 (9) | comments 0 | with audio podcast

Breakthrough in how pancreatic cancer cells ingest nutrients points to new drug target

In a landmark cancer study published online in Nature, researchers at NYU School of Medicine have unraveled a longstanding mystery about how pancreatic tumor cells feed themselves, opening up new therapeutic possibilities for a ...

Cancer created May 13, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

SUMO wrestling cells reveal new protective mechanism target for stroke

Scientists investigating the interaction of a group of proteins in the brain responsible for protecting nerve cells from damage have identified a new target that could increase cell survival.

Medical research created May 17, 2013 | popularity 5 / 5 (1) | comments 0

Unleashing the watchdog protein

McGill University researchers have unlocked a new door to developing drugs to slow the progression of Parkinson's disease. Collaborating teams led by Dr. Edward A. Fon at the Montreal Neurological Institute and Hospital -The ...

Parkinson's & Movement disorders created May 09, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists show how nerve wiring self-destructs

Many medical issues affect nerves, from injuries in car accidents and side effects of chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the ...

Neuroscience created May 09, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers describe how breast cancer cells acquire drug resistance

A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death. The discovery provides new avenues ...

Cancer created May 07, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Individual efficacy of chemotherapies

The function of the mitochondria – also defined as "power plants" within the cells – is essential as to whether, and how, some chemotherapeutic agents take effect in tissue. Scientists at the Helmholtz ...

Cancer created May 10, 2013 | popularity not rated yet | comments 0

Research reveals cancer-suppressing protein 'multitasks'

The understanding of how a powerful protein called p53 protects against cancer development has been upended by a discovery by Walter and Eliza Hall Institute researchers.

Cancer created May 09, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

MicroRNA cooperation mutes breast cancer oncogenes

A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot ...

Cancer created May 07, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New light shed on early stage Alzheimer's disease

The disrupted metabolism of sugar, fat and calcium is part of the process that causes the death of neurons in Alzheimer's disease. Researchers from Karolinska Institutet in Sweden have now shown, for the first time, how important ...

Alzheimer's disease & dementia created Apr 22, 2013 | popularity 5 / 5 (5) | comments 1 | with audio podcast

New compound discovered that rapidly kills liver cancer

Scientists have identified a new compound that rapidly kills hepatocellular carcinoma (HCC) cells, the most common form of liver cancer and fifth most common cancer worldwide, while sparing healthy tissue. The compound, Factor ...

Cancer created Mar 14, 2012 | popularity 5 / 5 (20) | comments 0 | with audio podcast

'Very promising' treatment for Huntington disease discovered

Medical researchers at the University of Alberta have discovered a promising new therapy for Huntington disease that restores lost motor skills and may delay or stop the progression of the disease based on lab model tests, ...

Diseases, Conditions, Syndromes created Feb 13, 2012 | popularity 5 / 5 (9) | comments 1 | with audio podcast

Programmed cell death

Programmed cell-death (or PCD) is death of a cell in any form, mediated by an intracellular program. In contrast to necrosis, which is a form of cell-death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process which generally confers advantage during an organism's life-cycle. PCD serves fundamental functions during both plant and metazoa (multicellular animals) tissue development.

For more information about Programmed cell death, read the full article at Wikipedia.
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