News tagged with cell degeneration
Putting the brakes on Parkinson's: Anle138b prevents clumping of synunclein protein
The earliest signs of Parkinson's disease can be deceptively mild. The first thing that movie star Michael J. Fox noticed was twitching of the little finger of his left hand. For years, he made light of the ...
Parkinson's & Movement disorders
Apr 23, 2013 |
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Promoting muscle regeneration in a mouse model of muscular dystrophy
Duchenne muscular dystrophy (DMD) is a degenerative skeletal muscle disease caused by mutations in the protein dystrophin. Dystrophin functions to protect muscle cells from injury and loss of functional dystrophin results ...
Medical research
Apr 01, 2013 |
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Shedding light on early Parkinson's disease pathology
In a mouse model of early Parkinson's disease (PD), animals displayed movement deficits, loss of tyrosine-hydroxylase (TH)-positive fibers in the striatum, and astro-gliosis and micro-gliosis in the substantia nigra (SN), ...
Parkinson's & Movement disorders
Apr 01, 2013 |
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Engineer invents bionic eye to help the blind
(Medical Xpress)—For UCLA bioengineering professor Wentai Liu, more than two decades of visionary research burst into the headlines last month when the FDA approved what it called "the first bionic eye for the blind." ...
Ophthalmology
Mar 25, 2013 |
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Long-suspected cause of blindness from eye disease disproved
Vision scientists long have thought that lack of very long chain fatty acids in photoreceptor cells caused blindness in children with Stargardt type 3 retinal degeneration, an incurable eye disease. But researchers at the ...
Ophthalmology
Mar 11, 2013 |
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Tackling hearing loss
Some 16 per cent of European adults suffer from hearing loss that is severe enough to adversely affect their daily life. Hearing loss impacts on one's ability to communicate - to hear, process sound, and ...
Other
Feb 27, 2013 |
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Excess protein linked to development of Parkinson's disease
Researchers at the University of California, San Diego School of Medicine say overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons, starting with the ...
Parkinson's & Movement disorders
Feb 07, 2013 |
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New findings on heat shock proteins may shed light on variety of debilitating diseases
UCLA researchers, in a finding that runs counter to conventional wisdom, have discovered for the first time that a gene thought to express a protein in all cells that come under stress is instead expressed only in specific ...
Medical research
Jan 29, 2013 |
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Scientists discover 'needle in a haystack' for muscular dystrophy patients
(Medical Xpress)—Muscular dystrophy is caused by the largest human gene, a complex chemical leviathan that has confounded scientists for decades. Research conducted at the University of Missouri and described ...
Medical research
Jan 22, 2013 |
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Study of how eye cells become damaged could help prevent blindness
Light-sensing cells in the eye rely on their outer segment to convert light into neural signals that allow us to see. But because of its unique cylindrical shape, the outer segment is prone to breakage, which ...
Medical research
Jan 22, 2013 |
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New study sheds light on the complexity of gene therapy for congenital blindness
Independent clinical trials, including one conducted at the Scheie Eye Institute at the Perelman School of Medicine, have reported safety and efficacy for Leber congenital amaurosis (LCA), a congenital form of blindness caused ...
Genetics
Jan 22, 2013 |
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Transmission of tangles in Alzheimer's mice provides more authentic model of tau pathology
Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised ...
Neuroscience
Jan 15, 2013 |
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A quantum leap in gene therapy of Duchenne muscular dystrophy
Usually, results from a new study help scientists inch their way toward an answer whether they are battling a health problem or are on the verge of a technological breakthrough. Once in a while, those results ...
Medical research
Jan 15, 2013 |
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Another muscular dystrophy mystery solved; MU scientists inch closer to a therapy for patients
Approximately 250,000 people in the United States suffer from muscular dystrophy, which occurs when damaged muscle tissue is replaced with fibrous, bony or fatty tissue and loses function. Three years ago, University of Missouri ...
Medical research
Dec 07, 2012 |
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Study identifies a potential cause of Parkinson's disease
Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed ...
Parkinson's & Movement disorders
Nov 19, 2012 |
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