Team finds mechanism linking key inflammatory marker to cancer
In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.
Cancer
5 hours ago |
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New protein-targeting drug shows promise in early trial for patients with high-risk CLL
A new oral targeted drug, idelalisib (GS-1101), has the potential to stave off the need for additional treatments for relapsed or treatment-resistant chronic lymphocytic leukemia (CLL), according to a study led in part by ...
Cancer
May 17, 2013 |
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Study brings greater understanding of tumor growth mechanism
A study led by researchers from Plymouth University Peninsula Schools of Medicine and Dentistry has for the first time revealed how the loss of a particular tumour suppressing protein leads to the abnormal growth of tumours ...
Neuroscience
May 16, 2013 |
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Breakthrough in how pancreatic cancer cells ingest nutrients points to new drug target
In a landmark cancer study published online in Nature, researchers at NYU School of Medicine have unraveled a longstanding mystery about how pancreatic tumor cells feed themselves, opening up new therapeutic possibilities for a ...
Cancer
May 13, 2013 |
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Gene mutation as cause of breast and ovarian cancer
A change to the so-called TERT gene considerably increases the risk of breast and ovarian cancer. This is the result of a current, multicenter study in which the University Department of Gynaecology and the ...
Cancer
May 10, 2013 |
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Scientists define a new mechanism leading to tumor hypoxia
An article published recently in Tumor Microenvironment and Therapy - an open access journal by Versita, defines a novel mechanism of tumor hypoxia induced by the longitudinal gradient of residual oxygen along tumor vessel ...
Cancer
May 09, 2013 |
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New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice
(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...
Cancer
May 08, 2013 |
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Exercise could reduce bone tumor growth
(Medical Xpress)—Weight-bearing exercise, often prescribed to combat bone loss, might have anti-cancer effects. Cornell biomedical researchers report that mechanical stimulation of cancerous bone, in making ...
Cancer
May 07, 2013 |
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Researchers discover endogenous antibiotic in the brain
Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have discovered that immune cells in the brain can produce a substance that prevents bacterial growth: namely itaconic acid. ...
Medical research
May 06, 2013 |
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A tangle of talents untangles neurons
(Medical Xpress)—Two wrongs don't make a right, they say, but here's how one tangle can straighten out another.
Medical research
May 06, 2013 |
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Scientists discover new target for personalized cancer therapy
A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a ...
Cancer
May 02, 2013 |
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'Traffic' in our cells works both for and against us
A mechanism that permits essential substances to enter our cells while at the same time removing from them harmful components also has a "down side." This negative aspect prevents vital drugs, such as anti-cancer drugs, from ...
Medical research
May 01, 2013 |
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Study finds experimental drug inhibits growth in all stages of common kidney cancer
Researchers at Mayo Clinic's campus in Florida have discovered a protein that is overly active in every human sample of kidney cancer they examined. They also found that an experimental drug designed to block the protein's ...
Cancer
Apr 30, 2013 |
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Protein improves efficacy of tumor-killing enzyme
Scientists have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio, the online open-access journal of the American Societ ...
Cancer
Apr 30, 2013 |
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VEGF may not be relevant biomarker for advanced prostate cancer
The well-studied protein VEGF does not appear to have any prognostic or predictive value for men with locally advanced prostate cancer, researchers from the Department of Radiation Oncology at Thomas Jefferson University ...
Cancer
Apr 29, 2013 |
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