Poliovirus vaccine trial shows early promise for recurrent glioblastoma
An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report.
Cancer
May 21, 2013 |
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Finding a family for a pair of orphan receptors in the brain
Researchers at Emory University have identified a protein that stimulates a pair of "orphan receptors" found in the brain, solving a long-standing biological puzzle and possibly leading to future treatments for neurological ...
Medical research
May 21, 2013 |
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Preventing blood poisoning
Peptide molecules derived from the body's natural immune system can help boost the body's defence against life-threatening blood poisoning, joint University research has uncovered.
Medical research
May 17, 2013 |
4 / 5 (1) |
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Resistance to visceral leishmaniasis: New mechanisms involved
Researchers from CNRS, Université Toulouse III - Paul Sabatier and IRD have elucidated new molecular mechanisms involved in resistance to visceral leishmaniasis, a serious parasitic infection. They have shown that dectin-1 ...
Immunology
May 16, 2013 |
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Scientists find potential therapeutic target for Cushing's disease
Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this ...
Diseases, Conditions, Syndromes
May 07, 2013 |
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Researchers identify critical link in mammalian odor detection
Researchers at the Monell Center and collaborators have identified a protein that is critical to the ability of mammals to smell. Mice engineered to be lacking the Ggamma13 protein in their olfactory receptors were functionally ...
Neuroscience
May 06, 2013 |
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Effects of stress on brain cells offer clues to new anti-depressant drugs
Research from King's College London reveals the detailed mechanism behind how stress hormones reduce the number of new brain cells - a process considered to be linked to depression. The researchers identified a key protein ...
Neuroscience
May 06, 2013 |
3.9 / 5 (7) |
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Making cancer less cancerous: Blocking a single gene renders tumors less aggressive
Researchers at Johns Hopkins have identified a gene that, when repressed in tumor cells, puts a halt to cell growth and a range of processes needed for tumors to enlarge and spread to distant sites. The researchers hope that ...
Cancer
May 02, 2013 |
4.7 / 5 (10) |
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Study uses Botox to find new wrinkle in brain communication
National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel ...
Medical research
May 02, 2013 |
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Researchers look to mathematics, nature, to understand the immune system and its role in cancer
Can the patterns in tree branches or the meandering bends in a river provide clues that could lead to better cancer therapies? According to a new study from Virginia Commonwealth University Massey Cancer ...
Medical research
May 01, 2013 |
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T cells rely on 'rheostat' to help ensure that the immune response matches the threat
A properly functioning immune system is a lesson in balance, providing protection against disease without attacking healthy tissue. Work led by St. Jude Children's Research Hospital scientists and published recently in Nature Im ...
Immunology
Apr 30, 2013 |
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Tactics of new Middle East virus suggest treating by altering lung cells' response to infection
A new virus that causes severe breathing distress and kidney failure elicits a distinctive airway cell response to allow it to multiply. Scientists studying the Human Coronavirus-Erasmus Medical Center, which ...
Diseases, Conditions, Syndromes
Apr 30, 2013 |
5 / 5 (1) |
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Scientists make insulin-producing cells self-replicate
(Medical Xpress)—Scientists have discovered a hormone that causes the body's insulin-producing factories, beta cells, to churn out more of themselves. Having enough insulin is critical to regulating the amount of sugar ...
Medical research
Apr 29, 2013 |
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Mutant version of H5N1 flu virus found to be more preferential to human infection
(Medical Xpress)—An international team of bio-researchers has found that a mutant strain of the H5N1 influenza virus (created in a lab) has a 200-fold preference for binding with receptors in human cells, ...
Diseases, Conditions, Syndromes
Apr 25, 2013 |
5 / 5 (2) |
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Researchers identify new pathway, enhancing tamoxifen to tame aggressive breast cancer
Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen's secondary ...
Cancer
Apr 23, 2013 |
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