Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically ...
Mar 13, 2023
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51
A type of immune therapy called chimeric antigen receptor (CAR)-T cell therapy has revolutionized the treatment of multiple types of blood cancers but has shown limited efficacy against glioblastoma—the deadliest type of ...
Mar 13, 2023
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65
Estrogen is known to play an important role in the protection of women's hearts, but once women are postmenopausal and estrogen levels drop, they are at an increased risk of a number of diseases and conditions, including ...
Mar 10, 2023
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The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an increased susceptibility to viral ...
Mar 10, 2023
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For the first time, researchers examine the effects of gender-affirming androgen therapy on breast tissue in transgender men with single-cell resolution. Their results give an unprecedented look into the changes that occur ...
Mar 8, 2023
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141
The drug denosumab is currently used to treat osteoporosis and bone metastases. For more than a decade, its potential therapeutic benefit in the treatment of breast cancer has also been studied. However, due to conflicting ...
Mar 7, 2023
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5
In autoimmune encephalitis, a rare but serious and sometimes life-threatening inflammation of the central nervous system, the body's own defenses are directed against the central nervous system. This disease was first identified ...
Mar 3, 2023
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79
Controversies surrounding hormone therapy (HT) and its benefits and risks have dominated the women's health field for more than 2 decades. A large new study demonstrates that, despite some commonly held misperceptions, HT ...
Mar 1, 2023
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Blood cancer patients, especially when they relapse, have a poor prognosis, and generally do not survive very long. The last five years have seen success in treating these patients with Chimeric Antigen Receptor (CAR) T-cells—a ...
Feb 24, 2023
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50
Universitätsklinikum Erlangen is the first in the world to use CAR T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The disease is triggered by a malfunction in the ...
Feb 20, 2023
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