Senescent cells—those that have lost the ability to divide—accumulate with age and are key drivers of age-related diseases, such as cancer, dementia and cardiovascular disease. In a new study, a team led by University ...
Jun 30, 2022
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Valproic acid—a drug used to treat epilepsy, migraine, and bipolar disorder—can cause birth defects when taken during pregnancy. Now, a study publishing June 14 in the open access journal PLOS Biology by Bill Keyes of ...
Jun 14, 2022
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Destroying senescent cells in the aging stem cell niche enhances hippocampal neurogenesis and cognitive function in mice, researchers report January 20 in the journal Stem Cell Reports.
Jan 20, 2022
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A team of researchers affiliated with a large number of institutions in Japan has developed a vaccine that tricks the immune system into removing senescent cells. In their paper published in the journal Nature Aging, the ...
For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.
Dec 10, 2021
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Eliminating old, dysfunctional cells in human fat also alleviates signs of diabetes, researchers from UConn Health report. The discovery could lead to new treatments for Type 2 diabetes and other metabolic diseases.
Nov 22, 2021
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Chronic back pain affects upwards of 15 million adults in the US, racking up billions in healthcare costs and lost work days. Degeneration of the discs that cushion and support vertebrae, a common occurrence of aging, is ...
Sep 3, 2021
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Research from the Cancer Institute at the Japanese Foundation for Cancer Research (JFCR), which was published today in the leading international scientific journal Proceedings of the National Academy of Sciences, reveals ...
Aug 23, 2021
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Mammals have a poor ability to recover after a spinal cord injury, which can result in paralysis. A main reason for this is the formation of a complex scar associated with chronic inflammation that produces a cellular microenvironment ...
Jul 6, 2021
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New research from the University of Minnesota Medical School and colleagues at the Mayo Clinic reveals a possible new approach to preventing death and severe disease in elderly people infected with SARS-CoV-2.
Jun 8, 2021
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