Medications

How drugs can target the thick 'scar tissue' of pancreatic cancer

Pancreatic cancer is one of the deadliest cancers—only about one in eight patients survives five years after diagnosis. Those dismal statistics are in part due to the thick, nearly impenetrable wall of fibrosis, or scar ...

Medical research

Fighting fruit flies help researchers understand why we stay angry

It's one of those days. On the drive home from work, the car in the next lane cuts you off. You slam on the brakes, lay on the horn, and yell choice words at the offending driver. When you walk into your house half an hour ...

Medical research

Repairing nerve cells after injury and in chronic disease

Each year in the United States there are more than 3 million cases of peripheral neuropathy, wherein nerves outside of the brain and spinal cord are damaged and cause pain and loss of feeling in the affected areas. Peripheral ...

Genetics

Decoding cell fate: Key mechanism in stem cell switch identified

Stem cells can differentiate to replace dead and damaged cells. But how do stem cells decide which type of cell to become in a given situation? Using intestinal organoids, the group of Bon-Kyoung Koo at IMBA and the Institute ...

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