Mesomelic dysplasias are a group of rare genetic conditions characterized by extreme shortening of the long bones in the arms and legs. Despite several decades of research on these conditions, the exact cause of mesomelic ...
Aug 23, 2021
0
379
Yale researchers have discovered the underlying genetic cause of a rare childhood disorder that mimics inflammatory bowel disease, a finding that may help researchers uncover the roots of a host of other inflammatory and ...
Jul 29, 2021
0
436
A Ludwig Cancer Research study has found that inducing random chromosome instability (CIN) events in mice for as little as one week is enough to trigger harmful chromosomal patterns in cells that spur the formation of tumors.
Jul 16, 2021
0
34
A research group including Kobe University's Professor Takumi Toru (also a Senior Visiting Scientist at RIKEN Center for Biosystems Dynamics Research) and Assistant Professor Tamada Kota, both of the Physiology Division in ...
Jul 9, 2021
0
8
Drugs targeting the gene MAGEA3 may help block the growth of hepatocellular carcinoma (HCC), the most common type of primary liver cancer and one of the leading causes of cancer deaths in the country. That's one conclusion ...
Jun 24, 2021
0
6
The rarity of these syndromes, caused by damage to a gene named HUWE1, means very few children are affected. Of course, the low absolute numbers are little consolation for children who are born with a severe intellectual ...
Jun 17, 2021
0
3
New insight on the link between a gene called SORBS2 and congenital heart disease has been published today in eLife, with findings that may help explain the cause of the disease in some patients.
Jun 8, 2021
0
0
In animal models, iron deficient mothers had a greatly increased risk of having offspring with congenital heart disease (CHD).
Jun 8, 2021
0
0
Researchers at Karolinska Institutet have investigated the use of low dose venetoclax, an experimental drug, for the treatment of the heterogeneous cancer disease multiple myeloma in patients who had relapsed on standard ...
May 19, 2021
0
27
After the p53 tumor suppressor gene, the genes most frequently found mutated in cancer are those encoding two proteins of the SWI/SNF chromatin remodeling complex. This complex's function is to 'accommodate' the histones ...
May 14, 2021
0
16
