News tagged with clinical model
Primary component in turmeric kicks off cancer-killing mechanisms in human saliva
Curcumin, the main component in the spice turmeric, suppresses a cell signaling pathway that drives the growth of head and neck cancer, according to a pilot study using human saliva by researchers at UCLA's Jonsson Comprehensive ...
Cancer
Sep 13, 2011 |
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Research identifies inhibitor causing male pattern baldness and target for hair-loss treatments
Researchers from the Perelman School of Medicine at the University of Pennsylvania have identified an abnormal amount a protein called Prostaglandin D2 in the bald scalp of men with male pattern baldness, a discovery that ...
Medical research
Mar 21, 2012 |
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'Very promising' treatment for Huntington disease discovered
Medical researchers at the University of Alberta have discovered a promising new therapy for Huntington disease that restores lost motor skills and may delay or stop the progression of the disease based on lab model tests, ...
Diseases, Conditions, Syndromes
Feb 13, 2012 |
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Feeling hungry may protect the brain against Alzheimer's disease, study finds
The feeling of hunger itself may protect against Alzheimer's disease, according to study published today in the journal PLOS ONE. Interestingly, the results of this study in mice suggest that mild hunger ...
Alzheimer's disease & dementia
Apr 03, 2013 |
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Alzheimer's vaccine cures memory of mice
(Medical Xpress) -- A vaccine that slows the progression of Alzheimer's disease and other types of dementia has been developed by researchers at the University of Sydney's Brain and Mind Research Institute ...
Alzheimer's disease & dementia
Dec 09, 2011 |
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In reversing motor nerve damage, time is of the essence
When a motor nerve is severely damaged, people rarely recover full muscle strength and function. Neuroscientists from Children's Hospital Boston, combining patient data with observations in a mouse model, now show why. It's ...
Medical research
Oct 03, 2011 |
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New study sheds light on the complexity of gene therapy for congenital blindness
Independent clinical trials, including one conducted at the Scheie Eye Institute at the Perelman School of Medicine, have reported safety and efficacy for Leber congenital amaurosis (LCA), a congenital form of blindness caused ...
Genetics
Jan 22, 2013 |
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New strategy prevents rheumatoid arthritis in mice
Dana-Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved ...
Arthritis & Rheumatism
Feb 08, 2013 |
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Researchers create next-generation Alzheimer's disease model
A new genetically engineered lab rat that has the full array of brain changes associated with Alzheimer's disease supports the idea that increases in a molecule called beta-amyloid in the brain causes the ...
Alzheimer's disease & dementia
Apr 09, 2013 |
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Researchers report success in treating autism spectrum disorder
Using a mouse model of autism, researchers at the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center have successfully treated an autism spectrum disorder characterized by severe cognitive impairment.
Autism spectrum disorders
Jul 02, 2012 |
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Gene deletion drives more than a quarter of breast cancers
A new study shows that the lack of a certain gene occurs in almost 28 percent of human breast cancers, playing a role in some 60,000 breast cancer cases in the United States and 383,000 worldwide this year.
Genetics
Aug 15, 2012 |
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Umbilical cord cells outperform bone marrow cells in repairing damaged hearts
A study published this month by researchers at the University of Toronto and Toronto's Princess Margaret Hospital has shown that cells derived from the umbilical cord, "Human Umbilical Cord PeriVascular Cells" (HUCPVCs), ...
Medical research
Nov 15, 2012 |
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Identifying the molecular causes of vision loss in demyelinating disease
Demyelinating diseases, such as multiple sclerosis (MS), are frequently associated with the progressive loss of vision. The retinal nerve damage is thought to be caused by immune system-mediated inflammation; however, other ...
Ophthalmology
Jan 02, 2013 |
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Differences between 'marathon mice' and 'couch potato mice' reveal key to muscle fitness
Researchers discovered that small pieces of genetic material called microRNAs link the two defining characteristics of fit muscles: the ability to burn sugar and fat and the ability to switch between slow- ...
Medical research
May 08, 2013 |
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New mouse model may lead to new therapies for degenerative diseases
Most degenerative diseases begin with a gradual loss of specific cell types that progresses, eventually leading to symptoms. For example, in type I diabetes, hyperglycemia commonly develops when approximately 80 percent of ...
Medical research
May 16, 2011 |
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