News tagged with clopidogrel

Researchers study under-recognised and under-treated prothrombotic condition: High platelet reactivity despite treatment

Within the past decade, the variability in pharmacodynamic response and moderate antiplatelet efficacy of clopidogrel has raised major concerns, in particular because it is associated with an increased risk for ischemic events ...

Cardiology created May 06, 2013 | popularity not rated yet | comments 0

Shopping around brings steep prescription drug savings, report finds

(HealthDay News) —Prescription drug prices at U.S. pharmacies can vary widely, and failing to shop around could result in people overpaying by as much as $100 or more a month on average, depending on the ...

Medications created Mar 28, 2013 | popularity not rated yet | comments 0

Do blood thinners + stroke treatment = danger? Study indicates the risk is low

Millions of Americans take aspirin or other drugs every day to reduce their risk of heart attacks or other problems caused by blood clots.

Cardiology created Mar 13, 2013 | popularity not rated yet | comments 0 | with audio podcast

New drugs might give heart patients an edge

(HealthDay)—In the search for better medicines to safely help heart patients, clinical trials testing three new drugs appear to offer some promise.

Cardiology created Mar 11, 2013 | popularity 4 / 5 (1) | comments 0

Cangrelor superior to clopidogrel in CHAMPION PHOENIX trial

The experimental anti-clotting drug cangrelor solidly outperformed commonly used clopidogrel in a large global trial of patients who underwent coronary stent procedures, according to data from the phase III CHAMPION PHOENIX ...

Cardiology created Mar 11, 2013 | popularity not rated yet | comments 1

New anti-clotting drug more effective than current treatment

A new and experimental anti-clotting drug, cangrelor, proved better than the commonly used clopidogrel and was significantly more effective at preventing blood clots in a large trial of patients who underwent coronary stent ...

Cardiology created Mar 11, 2013 | popularity not rated yet | comments 0

Novel anti-clotting drug more effective than Plavix in coronary procedures, study says

(Medical Xpress)—An experimental drug has been shown to be significantly more effective at preventing blood clots during coronary stenting procedures compared to the anti-clotting agent now typically used, according to ...

Cardiology created Mar 11, 2013 | popularity not rated yet | comments 0 | with audio podcast

Major risks of dual and triple antithrombotic therapy in patients with newly diagnosed atrial fibrillation

According to Dr. Samy Suissa, Director of Clinical Epidemiology, Jewish General Hospital, and Professor of Epidemiology, McGill University in Montreal, Canada, "treating physicians need to consider the clinical effectiveness ...

Cardiology created Mar 05, 2013 | popularity not rated yet | comments 0

Prehospital antiplatelets improve graft intervention outcomes

(HealthDay)—Prehospital use of antiplatelet therapy, either aspirin/clopidogrel or dual antiplatelet therapy (DAPT), is associated with a lower incidence of major adverse cardiac events after saphenous ...

Cardiology created Jan 28, 2013 | popularity not rated yet | comments 0

Administration of clopidogrel prior to PCI associated with reduction in major cardiac events

Among patients scheduled for a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), pretreatment with the antiplatelet agent clopidogrel ...

Cardiology created Dec 18, 2012 | popularity not rated yet | comments 0 | with audio podcast

New study finds that 75 percent of patients taking popular blood-thinners are getting wrong dose

Cardiology researchers at the Intermountain Medical Center Heart Institute have found that approximately 75 percent of patients taking two common blood-thinning drugs may be receiving the wrong dosage levels, according to ...

Cardiology created Nov 06, 2012 | popularity 5 / 5 (1) | comments 0

Some heart patients may respond differently to anti-platelet drugs

The cause of heart attacks or strokes among some patients treated with anti-platelet drugs may be different than for patients who have undergone surgical procedures to restore blood flow, according to researchers at Duke ...

Cardiology created Nov 05, 2012 | popularity not rated yet | comments 0 | with audio podcast

Low responsiveness to clopidogrel predicts stent thrombosis, heart attack: But is not directly linked to death

Patients who receive a drug-eluting stent (DES) and demonstrate low levels of platelet inhibition are more likely to have blood clots form on the stent and suffer a possible heart attack; conversely, patients with higher ...

Cardiology created Oct 25, 2012 | popularity not rated yet | comments 0

Researchers ID potential patient population who may benefit from novel anti-platelet treatment

Prasugrel, a novel anti-platelet therapy, is used to prevent recurrent cardiovascular events in patients who have had a prior heart attack, suffer severe chest pain and have been treated with coronary artery procedures (revascularization).

Cardiology created Oct 24, 2012 | popularity not rated yet | comments 0

Year of taking risky blood thinners may be unnecessary after stent surgery

(HealthDay)—A full year of aggressive anti-clotting therapy—which can lead to heavy bleeding—may not be needed after surgery to implant a drug-coated cardiac stent, two new studies suggest.

Cardiology created Sep 20, 2012 | popularity not rated yet | comments 0 | with audio podcast

Clopidogrel

Clopidogrel is an oral, thienopyridine class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It is marketed by Bristol-Myers Squibb and Sanofi-Aventis under the trade name Plavix. The drug works by irreversibly inhibiting a receptor called P2Y12, an adenosine diphosphate ADP chemoreceptor. Adverse effects include hemorrhage, severe neutropenia, and thrombotic thrombocytopenic purpura (TTP).

For more information about Clopidogrel, read the full article at Wikipedia.
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