News tagged with clopidogrel

Anti-clotting drugs yield similar results

The first trial to study patients with acute coronary syndrome who do not undergo coronary stenting or bypass surgery found no significant difference between two anti-clotting drugs – prasugrel and clopidogrel – in preventing ...

Cardiology created Aug 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers study under-recognised and under-treated prothrombotic condition: High platelet reactivity despite treatment

Within the past decade, the variability in pharmacodynamic response and moderate antiplatelet efficacy of clopidogrel has raised major concerns, in particular because it is associated with an increased risk for ischemic events ...

Cardiology created May 06, 2013 | popularity not rated yet | comments 0

Novel anti-platelet therapy reduces risk of cardiac events in patients with history of heart attack

According to new research from Brigham and Women's Hospital (BWH), adding vorapaxar, an investigational platelet blocker, to standard antiplatelet therapy significantly reduces the long-term risk of recurrent cardiovascular ...

Cardiology created Aug 27, 2012 | popularity not rated yet | comments 0

Aspirin as good as Plavix for poor leg circulation: study

(HealthDay) -- Aspirin works as well as Plavix in patients with blocked leg arteries, a new European study finds.

Cardiology created Feb 22, 2012 | popularity 5 / 5 (1) | comments 1

Novel anti-clotting drug more effective than Plavix in coronary procedures, study says

(Medical Xpress)—An experimental drug has been shown to be significantly more effective at preventing blood clots during coronary stenting procedures compared to the anti-clotting agent now typically used, according to ...

Cardiology created Mar 11, 2013 | popularity not rated yet | comments 0 | with audio podcast

Year of taking risky blood thinners may be unnecessary after stent surgery

(HealthDay)—A full year of aggressive anti-clotting therapy—which can lead to heavy bleeding—may not be needed after surgery to implant a drug-coated cardiac stent, two new studies suggest.

Cardiology created Sep 20, 2012 | popularity not rated yet | comments 0 | with audio podcast

New drugs might give heart patients an edge

(HealthDay)—In the search for better medicines to safely help heart patients, clinical trials testing three new drugs appear to offer some promise.

Cardiology created Mar 11, 2013 | popularity 4 / 5 (1) | comments 0

New anti-clotting drug more effective than current treatment

A new and experimental anti-clotting drug, cangrelor, proved better than the commonly used clopidogrel and was significantly more effective at preventing blood clots in a large trial of patients who underwent coronary stent ...

Cardiology created Mar 11, 2013 | popularity not rated yet | comments 0

Complications in patients undergoing percutaneous coronary intervention tend to occur within first 30 days

Percutaneous coronary intervention (PCI), also known as coronary angioplasty or angioplasty, is a procedure used to treat acute coronary syndromes. PCI involves opening a blocked blood vessel by threading and inflating a ...

Cardiology created Mar 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

Do blood thinners + stroke treatment = danger? Study indicates the risk is low

Millions of Americans take aspirin or other drugs every day to reduce their risk of heart attacks or other problems caused by blood clots.

Cardiology created Mar 13, 2013 | popularity not rated yet | comments 0 | with audio podcast

Allergy to Plavix can be overcome: study

Allergies to Plavix, also know by its chemical name, Clopidogrel occur in about six percent of patients given the drug, vital for the prevention of life-threatening stent thrombosis after angioplasty and percutaneous coronary ...

Medications created Jan 16, 2012 | popularity not rated yet | comments 0

Prehospital antiplatelets improve graft intervention outcomes

(HealthDay)—Prehospital use of antiplatelet therapy, either aspirin/clopidogrel or dual antiplatelet therapy (DAPT), is associated with a lower incidence of major adverse cardiac events after saphenous ...

Cardiology created Jan 28, 2013 | popularity not rated yet | comments 0

Clopidogrel after MI less effective in diabetes patients

(HealthDay)—Clopidogrel therapy following a heart attack does less to reduce the risk of death in patients with diabetes than in those without diabetes, according to a study published in the Sept. 5 issue ...

Diabetes created Sep 05, 2012 | popularity not rated yet | comments 0

Plavix's new generic status could be boon for patients

(HealthDay) -- The blockbuster drug Plavix (clopidogrel), used to prevent clotting in some heart patients, will go off patent in the United States on Thursday, making it considerably more affordable.

Medications created May 15, 2012 | popularity not rated yet | comments 0

Aspirin-clopidogrel no better than aspirin alone for patients with lacunar stroke

Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, ...

Cardiology created Aug 29, 2012 | popularity not rated yet | comments 0 | with audio podcast

Clopidogrel

Clopidogrel is an oral, thienopyridine class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It is marketed by Bristol-Myers Squibb and Sanofi-Aventis under the trade name Plavix. The drug works by irreversibly inhibiting a receptor called P2Y12, an adenosine diphosphate ADP chemoreceptor. Adverse effects include hemorrhage, severe neutropenia, and thrombotic thrombocytopenic purpura (TTP).

For more information about Clopidogrel, read the full article at Wikipedia.
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