White matter in the brain that was previously implicated in animal studies has now been suggested to be specifically impaired in the brains of people with addiction to cocaine or heroin, according to a study conducted by ...
Oct 6, 2022
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Researchers have found that blocking certain acetylcholine receptors in the lateral habenula (LHb), an area of the brain that balances reward and aversion, made it harder to resist seeking cocaine in a rat model of impulsive ...
Jun 28, 2022
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Contrary to common thinking, cocaine triggers an addiction in only 20 percent of consumers. But what happens in their brains when they lose control of their consumption? Thanks to a recent experimental method, neuroscientists ...
Sep 9, 2021
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An emotion regulation strategy known as cognitive reappraisal helped reduce the typically heightened and habitual attention to drug-related cues and contexts in cocaine-addicted individuals, a study by Mount Sinai researchers ...
May 31, 2021
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A new study explains how cocaine modifies functions in the brain revealing a potential target for therapies aimed at treating cocaine addiction. The study was published this week in Cell Reports.
Apr 22, 2020
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Approximately 1.5 million Americans use cocaine in a given year, according to the National Institute on Drug Abuse. Many are repeat users. Unfortunately, there are currently no FDA-approved medicinal treatments for cocaine ...
Mar 18, 2019
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Women's hormonal cycles may not only make them more prone to drug addiction but also more affected by triggers that lead to relapse, a new Vanderbilt University study revealed. The findings are especially significant since ...
Feb 9, 2019
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A team with members affiliated with several institutions in the U.S. has found that disabling the gene responsible for the production of the protein tyrosine phosphatase D (PTPRD) caused test mice to self-administer less ...
There are no approved medications to treat either cocaine addiction or overdose. Frequent users tend to become less and less sensitive to the drug, leading to stronger or more frequent doses. The typical result is addiction. ...
Sep 17, 2018
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Cocaine relapse was significantly reduced in a preclinical model when brain-derived neurotropic factor (BDNF) was applied to the nucleus accumbens deep in the brain immediately before cocaine-seeking behavior, report investigators ...
Aug 3, 2018
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