DNA from cystic fibrosis patients with and without chronic infections points to unsuspected mutation
(Medical Xpress) -- Comparing the DNA from patients at the best and worst extremes of a health condition can reveal genes for resistance and susceptibly. This approach discovered rare variations in the DCTN4 ...
Genetics
Jul 08, 2012 |
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Discovery holds potential in destroying drug-resistant bacteria
Through the serendipity of science, researchers at the University of Pittsburgh have discovered a potential treatment for deadly, drug-resistant bacterial infections that uses the same approach that HIV uses to infect cells. ...
Medical research
May 07, 2013 |
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Protein's well-known cousin sheds light on its gout-linked relative
Johns Hopkins scientists have found out how a gout-linked genetic mutation contributes to the disease: by causing a breakdown in a cellular pump that clears an acidic waste product from the bloodstream. By comparing this ...
Medical research
Apr 08, 2013 |
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Genome study reveals human-to-human spread of multidrug resistant mycobacterial infection
Using DNA tracking of an outbreak among cystic fibrosis patients at a treatment centre in the UK, the scientists identified frequent patient-to-patient transmission despite stringent infection control measures.
Diseases, Conditions, Syndromes
Mar 28, 2013 |
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Antibiotic may provide benefit for treatment of respiratory disorder
Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic erythromycin resulted in improvement in symptoms but also increased the risk of antibiotic resistance, according to a ...
Diseases, Conditions, Syndromes
Mar 26, 2013 |
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Scientists identify new strategy to fight deadly infection in cystic fibrosis
New research suggests that lowering excessive levels of a protein in immune system cells could be a strategy to clear an infection that is deadly to patients with cystic fibrosis (CF).
Medical research
Jan 23, 2013 |
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Impaired blood vessel function found in cystic fibrosis patients
The first evidence of blood vessel dysfunction has been found in a small cohort of generally healthy young people with cystic fibrosis, researchers report.
Medical research
Nov 26, 2012 |
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Researchers report first effective treatment of tumors arising from common genetic disease NF1
Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially life-threatening tumors often found in children.
Cancer
Nov 01, 2012 |
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Healthy lungs' microbes focus of study on cystic fibrosis
(Medical Xpress)—Healthy people's lungs are home to a diverse community of microbes that differs markedly from the bacteria found in the lungs of cystic fibrosis patients. That's the result of new research from Stanford ...
Medical research
Sep 27, 2012 |
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New proteins to clear the airways in cystic fibrosis and COPD
University of North Carolina scientists have uncovered a new strategy that may one day help people with cystic fibrosis and chronic obstructive pulmonary disorder better clear the thick and sticky mucus that clogs their lungs ...
Diseases, Conditions, Syndromes
Jul 13, 2012 |
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Gene variations linked to intestinal blockage in newborns with cystic fibrosis
University of North Carolina at Chapel Hill researchers working as part of the International Cystic Fibrosis Consortium have discovered several regions of the genome that may predispose cystic fibrosis (CF) patients to develop ...
Genetics
Apr 01, 2012 |
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Decade-long study raises new questions about antibiotic use for cystic fibrosis
When it comes to treating cystic fibrosis, the current standard of aggressive antibiotic treatments may not always be the best answer, a decade-long study led by researchers at the University of Michigan has ...
Medical research
Mar 26, 2012 |
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Drug approved to treat cystic fibrosis' root cause
The first drug that treats the root cause of cystic fibrosis won approval Tuesday, offering a life-changing treatment for a handful of patients with the deadly illness and broader hope for thousands more patients with the ...
Medications
Jan 31, 2012 |
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Study identifies genome regions that could influence severity of cystic fibrosis
A team of researchers, including a number from the University of North Carolina at Chapel Hill School of Medicine, have pinpointed regions of the genome that contribute to the debilitating lung disease that is the hallmark ...
Genetics
May 23, 2011 |
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Scientists discover potential new target in fight against 'superbug'
University of Cambridge researchers have discovered how an antibiotic-resistant superbug exploits oxygen-limited conditions in the lungs of patients with severe respiratory disease to thrive.
Medical research
Jan 29, 2013 |
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