News tagged with disease pathogenesis
Mast cells have critical role in initializing pulmonary fibrosis
Pulmonary fibrosis is a chronic, deadly disease that affects five million people worldwide. It is irreversible, its cause is poorly understood, and it has a median survival of only about 3 years. A new study ...
Medical research
Apr 11, 2013 |
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Ranibizumab may prevent retinal detachment side effect
Proliferative vitreoretinopathy (PVR), or the formation of scar tissue in the eye, is a serious, sight-threatening complication in people recovering from surgical repair of retinal detachment. PVR is difficult to predict, ...
Ophthalmology
Apr 09, 2013 |
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New structural insight into neurodegenerative disease
A research team from the Korea Advanced Institute of Science and Technology (KAIST) released their results on the structure and molecular details of the neurodegenerative disease-associated protein Ataxin-1. ...
Genetics
Mar 14, 2013 |
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Researchers trick bacteria to deliver a safer vaccine
(Medical Xpress)—Vaccines that employ weakened but live pathogens to trigger immune responses have inherent safety issues but Yale researchers have developed a new trick to circumvent the problem—using ...
Medical research
Mar 13, 2013 |
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Providing brain cells with the 3rd dimension to grow outside the body
Researchers at Sahlgrenska Academy in collaboration with Chalmers University of Technology developed a unique Bioactive3D culture system for brain cells. This system gives new possibilities to study cell-cell ...
Medical research
Jan 25, 2013 |
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Depressive symptoms tied to doubled risk for Crohn's
(HealthDay)—Depressive symptoms are associated with a two-fold increase in risk of Crohn's disease (CD) but not ulcerative colitis (UC), according to research published in the January issue of Clinical Ga ...
Psychology & Psychiatry
Jan 16, 2013 |
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New research discovery provides therapeutic target for ALS
Research led by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, has found that the ability of a protein made by a gene called FUS to bind to RNA is essential to the development ...
Genetics
Dec 19, 2012 |
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Identification of mutations common to half of all liver cancers provides leads for new therapeutics
Liver cancer is the sixth most common cancer worldwide and the third leading cause of cancer-associated deaths. Yet even for such a frequent and deadly disease, the pathogenesis of this cancer remains obscure. ...
Cancer
Nov 16, 2012 |
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Researchers determine how inflammatory cells function, setting stage for future remedies
A research team led by investigators at New York University and NYU School of Medicine has determined how cells that cause inflammatory ailments, such as Crohn's disease, multiple sclerosis, and arthritis, differentiate from ...
Inflammatory disorders
Sep 26, 2012 |
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Central centrifugal cicatricial alopecia pathogenesis studied
(HealthDay)—Protease-activated receptor 2 (PAR-2), which is activated by cowhage, may play a role in central centrifugal cicatricial alopecia (CCCA), the most common cause of scarring hair loss in African-American ...
Cancer
Sep 21, 2012 |
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Zebra fish point the way towards new therapies for amyotrophic lateral sclerosis
Leuven scientists (VIB/KU Leuven) are using zebrafish as a model in their search for genes that play a role in the mechanism of amyotrophic lateral sclerosis (ALS). As a result, they have identified a molecule that could ...
Diseases, Conditions, Syndromes
Aug 27, 2012 |
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Scientists identify likely predictors of hepatitis C severity: viral evolution and host protein levels
(Medical Xpress) -- Scientists at the National Institutes of Health have identified several factors in people infected with the hepatitis C virus that may predict whether the unusually rapid progression of disease from initial ...
Diseases, Conditions, Syndromes
Jul 23, 2012 |
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Mice infected with Toxoplasma gondii parasite show Alzheimer's improvements
The parasite Toxoplasma gondii has some favorable effects on the pathogenesis and progression of a mouse model of Alzheimer's disease, reports a Mar. 21 study in the open access journal PLoS ONE.
Medical research
Mar 21, 2012 |
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New findings contradict dominant theory in Alzheimer's disease
For decades the amyloid hypothesis has dominated the research field in Alzheimer's disease. The theory describes how an increase in secreted beta-amyloid peptides leads to the formation of plaques, toxic clusters of damaged ...
Neuroscience
Oct 28, 2011 |
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Controlling cell death prevents skin inflammation
The outer layer of the skin, called the epidermis, forms a critical physical and immunological wall that serves as the body's first line of defense against potentially harmful microorganisms. Most of the epidermis consists ...
Medical research
Oct 13, 2011 |
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