Immunology

Study identifies two different regulatory T cell populations

A regulatory class of human T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity, according to a new study led by Children's Hospital of Philadelphia (CHOP). ...

Diseases, Conditions, Syndromes

Why severe fatty liver leads to liver damage

In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...

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