News tagged with dna alterations
Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...
Cancer
May 06, 2013 |
not rated yet |
0
Scientists find mutation driving pediatric brain tumors
A type of low-grade but sometimes lethal brain tumor in children has been found in many cases to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors, report scientists at ...
Genetics
Apr 30, 2013 |
5 / 5 (1) |
0
|
Three mutations at BRCA1 gene responsible for breast and ovarian hereditary cancer
Researchers of the hereditary cancer research group at the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute of Oncology (ICO) conducted a functional and structural study of seven missense variants ...
Cancer
Apr 18, 2013 |
not rated yet |
0
Unique study reveals genetic 'spelling mistakes' that increase the risk of common cancers
More than 80 genetic 'spelling mistakes' that can increase the risk of breast, prostate and ovarian cancer have been found in a large, international research study within the framework of the EU Network COGS. For the first ...
Cancer
Mar 27, 2013 |
not rated yet |
0
Exposure to violence, gene changes linked to asthma in Puerto Rican children
Puerto Rican children who have asthma are more likely to be exposed to violence and to have changes in a gene that is associated with stress, according to a new study led by researchers at Children's Hospital of Pittsburgh ...
Diseases, Conditions, Syndromes
Mar 19, 2013 |
not rated yet |
0
Discovery of new class of damage-prone DNA regions could lead to better cancer treatments
Cancer is thought to arise from DNA damage at fragile sites in the genome. A study published by Cell Press on January 24th in the journal Cell reveals a new class of fragile sites that contributes to DNA ...
Cancer
Jan 24, 2013 |
5 / 5 (1) |
0
|
Scientists pair blood test and gene sequencing to detect cancer
Scientists at the Johns Hopkins Kimmel Cancer Center have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients ...
Cancer
Nov 28, 2012 |
not rated yet |
0
|
A mother's nutrition—before pregnancy—may alter the function of her children's genes
Everyone knows that what mom eats when pregnant makes a huge difference in the health of her child. Now, new research in mice suggests that what she ate before pregnancy might be important too. According to a new research ...
Genetics
Sep 20, 2012 |
3 / 5 (2) |
0
|
In lung cancer, smokers have 10 times more genetic damage than never-smokers
Lung cancer patients with a history of smoking have 10 times more genetic mutations in their tumors than those with the disease who have never smoked, according to a new study from Washington University School of Medicine ...
Cancer
Sep 13, 2012 |
5 / 5 (2) |
0
ENCODE project: Researchers catalogue functional elements of the genome
Most of the DNA alterations that are tied to disease do not alter protein-coding genes, but rather the "switches" that control them. Characterizing these switches is one of many goals of the ENCODE project ...
Genetics
Sep 05, 2012 |
5 / 5 (3) |
1
|
Team creates a unique mouse model for the study of aplastic anaemia
Aplastic anaemia is characterised by a reduction in the number of the bone marrow cells that go on to form the different cell types present in blood (essentially red blood cells, white blood cells and platelets). In most ...
Medical research
Aug 29, 2012 |
not rated yet |
0
Existing drugs offer new treatment options for high-risk childhood leukemia subtype
Scientists have identified new genetic alterations underlying a high-risk subtype of the most common childhood cancer that could be effectively targeted with existing leukemia therapies.
Cancer
Aug 13, 2012 |
not rated yet |
0
|
New melanoma driver genes found in largest DNA sequencing study to date
(Medical Xpress) -- Yale Cancer Center geneticists, biochemists, and structural biologists have painted the most comprehensive picture yet of the molecular landscape of melanoma, a highly aggressive and often ...
Genetics
Jul 29, 2012 |
5 / 5 (4) |
0
|
Scientists find that chromosomal abnormalities are associated with aging and cancer
(Medical Xpress) -- Two new studies have found that large structural abnormalities in chromosomes, some of which have been associated with increased risk of cancer, can be detected in a small fraction of people without a ...
Genetics
May 08, 2012 |
4.8 / 5 (5) |
0
|
Patients with rare diseases to get DNA sequenced at no charge
Rare genetic diseases, long overlooked because they affect relatively few people, are getting new attention. Scientists at Washington University School of Medicine in St. Louis are reaching out to patient ...
Genetics
Mar 01, 2012 |
5 / 5 (2) |
1
