News tagged with dna damage
Related topics: cancer cells , cells , dna repair , breast cancer , cancer
Alcohol metabolism causes DNA damage and triggers a breast cancer-related DNA damage response
Alcohol is known to be carcinogenic to humans in the upper aerodigestive tract, liver, colorectum, and the female breast. Evidence suggests that acetaldehyde, the primary metabolite of alcohol, plays a major role in alcohol-related ...
Health
Sep 15, 2011 |
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Key function of mutation in hereditary breast and ovarian cancer gene discovered
It is widely known that mutations in the breast cancer susceptibility 1 (BRCA1) gene significantly increase the chance of developing breast and ovarian cancers, but the mechanisms at play are not fully understood. Now, researchers ...
Genetics
Sep 01, 2011 |
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At last, a reason why stress causes DNA damage
For years, researchers have published papers that associate chronic stress with chromosomal damage.
Medical research
Aug 21, 2011 |
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Study: New process that can save at-risk cancer patients is effective and significantly less costly
People at risk for a certain form of colon and other types of cancer may soon have a better chance at surviving or even avoiding the diseases, thanks to a new study done by the Intermountain Clinical Genetics Institute at ...
Cancer
Aug 16, 2011 |
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Stem cell mobilization therapy found to be safe for bone marrow donors
According to a study published in Blood, the Journal of the American Society of Hematology (ASH), researchers have reported that administration of granulocyte colony-stimulating factor (G-CSF), a drug that releases stem cells f ...
Medical research
Aug 11, 2011 |
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Targeting PTEN may prevent skin cancer
Scientists believe they have identified a role for PTEN, a known tumor suppressor, in removing DNA damage derived from UVB radiation, a known risk factor for non-melanoma skin cancer, according to a study published in Cancer Re ...
Cancer
Jul 26, 2011 |
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Researchers discover possible drug targets for common non-Hodgkin's lymphoma
Researchers at the University of Maryland School of Medicine have discovered a novel interaction between two proteins involved in regulating cell growth that could provide possible new drug targets for treating diffuse large ...
Cancer
Jul 19, 2011 |
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Study examines relationship of acculturation with sun-safe behaviors of US Latinos
Among Latinos living in the United States, acculturation is associated with sunscreen use, but not with use of sun-protective clothing, according to a report in the July issue of Archives of Dermatology.
Cancer
Jul 18, 2011 |
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Excess alcohol could damage our DNA
Researchers from the Medical Research Council (MRC) have uncovered for the first time how excess alcohol can cause irreparable damage to our DNA. In a new study published in the journal Nature today, MRC scientists also d ...
Health
Jul 07, 2011 |
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The genome guardian's dimmer switch: Regulating p53 is a matter of life or death
Scientists at the Salk Institute for Biological Studies have found clues to the functioning of an important damage response protein in cells. The protein, p53, can cause cells to stop dividing or even to commit suicide when ...
Genetics
Jun 30, 2011 |
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Blocking molecular target could make more cancers treatable with PARP inhibitors
BOSTON--Researchers at Dana-Farber Cancer Institute have demonstrated a molecular strategy they say could make a much larger variety of tumors treatable with PARP inhibitors, a promising new class of cancer drugs.
Cancer
Jun 29, 2011 |
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Premature aging caused by some HIV drugs, study shows
A class of anti-retroviral drugs commonly used to treat HIV, particularly in Africa and low income countries, can cause premature ageing, according to research published today in the journal Nature Genetics. The study shows ...
Genetics
Jun 26, 2011 |
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Malaria vaccination strategy provides model for superior protection
Malaria is a devastating disease caused by the Plasmodium parasite which is transmitted to humans by infected mosquitoes. Hundreds of millions of new cases of malaria are reported each year, and there are more than 750,000 ...
Medical research
Jun 15, 2011 |
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Cancer protein discovery may aid radiation therapy
Scientists at Dana-Farber Cancer Institute have uncovered a new role for a key cancer protein, a finding that could pave the way for more-effective radiation treatment of a variety of tumors.
Cancer
Jun 09, 2011 |
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Genetics of melanoma chemoresistance
Malignant melanoma is a highly aggressive and notoriously chemoresistant form of cancer. In a new paper, Ohanna et al. reveal that anti-melanoma drugs may, paradoxically, induce a senescence-associated secretory profile ("secretome") ...
Cancer
Jun 06, 2011 |
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