Oncology & Cancer
FDA approves cancer drug for personalized immunotherapy approach
Earlier this week, for the first time, a drug was FDA-approved for cancer based on disease genetics rather than type.
May 26, 2017
0
90
News tagged with dna replication
Genetics
Gene discovery sheds light on growth defects linked to dwarfism
A new study shows how errors in a specific gene can cause growth defects associated with a rare type of dwarfism.
Feb 13, 2017
0
22
Oncology & Cancer
Fission yeast may be used to find the next cancer cure
Cancer is a notoriously difficult disease to treat. Not only do a wide variety of cancers exist, requiring specialized treatments for each type, but cancer cells within an individual can morph and render previously potent ...
Oct 21, 2016
0
1
Oncology & Cancer
New molecular mechanism revealed for genetic mutations in aggressive cancer cells
Scientists at the University of Birmingham have described a previously-unknown molecular mechanism that could lead to the genetic mutations seen in certain types of aggressive cancer cells, involving a cell's own transcription ...
Oct 11, 2016
0
1
Genetics
Selective protection of genetic information by epigenetic system
DNA is replicated to pass genetic information to the daughter cells during cell proliferation. Replication errors, if not repaired, can lead to genetic mutations. For an individual organism, some DNA mutations may cause disease, ...
Aug 29, 2016
0
0
Genetics
Unexplained developmental disorder linked to gene involved in essential cellular processes
A neurodevelopmental disorder for which there was no known cause has been linked to SON, a gene that is involved in essential mechanisms a cell uses to translate DNA into protein, as well as in DNA replication and cell division. ...
Aug 18, 2016
0
0
Oncology & Cancer
Uncovering a new principle in chemotherapy resistance in breast cancer
A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes. The findings, ...
Jul 20, 2016
0
31
Oncology & Cancer
Researchers report breakthrough inhibition of colon tumors in mice models
Scientists from the Institute for Basic Science (IBS) have successfully inhibited the growth of colon tumors in mice with mismatch repair deficiency. The research team, headed by the Center's director MYUNG Kyungjae, made ...
Jun 15, 2016
0
13
Genetics
Gene linked to youthful appearance may help solve ageing puzzle
How long you live depends in part on the genes you inherit. For example, those suffering from Werner's syndrome have inherited two defective copies of a gene coding for an enzyme that is involved in DNA replication and repair.
May 2, 2016
0
70
Medical research
Study pinpoints mechanism that allows cells with faulty DNA to reproduce
When it comes to replicating their DNA so they can propagate, normal cells are perfectionists. Cancer cells, on the other hand, have no problem tolerating mistakes while copying their DNA. In fact, messed-up DNA is a big ...
Apr 28, 2016
0
80
