News tagged with dna variation

Cancer risk linked to DNA 'wormholes'

Single-letter genetic variations within parts of the genome once dismissed as 'junk DNA' can increase cancer risk through wormhole-like effects on far-off genes, new research shows.

Feb 19, 2015
popularity 5 / 5 (4) | comments 0

New tool pinpoints genetic sources of disease

Many diseases have their origins in either the genome or in reversible chemical changes to DNA known as the epigenome. Now, results of a new study from Johns Hopkins scientists show a connection between these two "maps." ...

Mar 20, 2014
popularity 4.3 / 5 (4) | comments 0

Research sheds new light on heritability of disease

A group of international researchers, led by a research fellow in the Harvard Medical School-affiliated Institute for Aging Research at Hebrew SeniorLife, published a paper today in Cell describing a study aimed at better ...

Jan 16, 2014
popularity 4.5 / 5 (2) | comments 0

Researching the roles of rare genetic variants in disease

As scientists work toward further personalizing medical treatment through genomics, heritability—the proportion of observed variation in a particular trait that can be attributed to inherited genetic factors—is key to ...

Nov 15, 2013
popularity not rated yet | comments 0

Methylation linked to metabolic disease

(Medical Xpress)—In the first in-depth analysis of DNA methylation in fat, a process that affects the regulation of genes, researchers have linked regions of methylation to metabolic traits such as high ...

Nov 11, 2013
popularity 4.5 / 5 (4) | comments 0

New tool enhances the search for genetic mutations

Concealed within the vastness of the human genome, (comprised of some 3 billion base pairs), mutations are commonplace. While the majority of these appear to have neutral effect on human health, many others ...

Aug 25, 2013
popularity 5 / 5 (1) | comments 0