Genetics
More than 260,000 Penn Medicine patients have agreed to share their DNA for research
Any changes in your medications or allergies? Check. New health issues since your last visit? Check.
Dec 4, 2023
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News tagged with dna
Diseases, Conditions, Syndromes
Antiviral therapy favors a lower risk of liver cirrhosis in HBeAg-negative chronic hepatitis B
New research delves into a traditionally overlooked category of chronic hepatitis B (CHB) patients. While those who are HBeAg-negative with normal ALT levels have been considered low-risk and often excluded from immediate ...
Dec 1, 2023
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Oncology & Cancer
Researchers exploit DNA amplification in cancer to halt chemoresistance
Cancer drug resistance remains a leading reason why treatments for specific cancers eventually do not work. A team of Stony Brook University researchers led by Gábor Balázsi, Ph.D., have been testing drug resistance with ...
Nov 28, 2023
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Genetics
Unlocking genetic mysteries: DNA methylation of gene silencers sheds light on disease variation
Professor Asaf Hellman and his research team at the Hebrew University-Hadassah Medical School have unveiled new findings in the realm of methylation-directed regulatory networks. Their study sheds light on the mechanisms ...
Nov 28, 2023
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Oncology & Cancer
CRISPR-powered 'cancer shredding' technique opens new possibility for treating most common and deadly brain cancer
The gene-editing technology CRISPR shows early promise as a therapeutic strategy for the aggressive and difficult-to-treat brain cancer known as primary glioblastoma, according to findings of a new study from Gladstone Institutes.
Nov 27, 2023
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Oncology & Cancer
Cancer blood tests jumpstart diagnoses and targeted therapy
New research led by a UC Davis Comprehensive Cancer Center clinical scientist shows blood tests used to hunt for cancer DNA may help detect cancers faster and guide the use of targeted therapies. The results of the study ...
Nov 22, 2023
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Oncology & Cancer
Nutrient found in beef and dairy improves immune response to cancer: Study
Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to ...
Nov 22, 2023
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Genetics
New study reveals unexpected consequences of CRISPR-Cas9 gene editing
A new study by Claudia Kutter's research group at the Department of Microbiology, Tumor and Cell Biology (MTC) has identified potential pitfalls in the use of the gene editing technique CRISPR-Cas9, a gene scissors that is ...
Nov 21, 2023
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Oncology & Cancer
Research finds correlation between biomarker HSD3B1 and resistance to combined hormone therapy and radiotherapy
Men with a particular genetic subtype of the steroid biosynthesis enzyme HSD3B1 may exhibit resistance to combined radiation and hormone therapy for prostate cancer, according to new Cleveland Clinic-led research published ...
Nov 20, 2023
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Oncology & Cancer
Genomic tug of war could boost cancer therapy
Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant ...
Nov 16, 2023
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