News tagged with dopamine

Related topics: brain , parkinson s disease , brain cells , attention deficit hyperactivity disorder , biological psychiatry

Turning off depression in the brain

Scientists have traced vulnerability to depression-like behaviors in mice to out-of-balance electrical activity inside neurons of the brain's reward circuit and experimentally reversed it – but there's ...

Apr 17, 2014
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Dopamine and hippocampus

Bruno Giros, PhD, a researcher at the Douglas Mental Health University Institute and a professor in the Department of Psychiatry at McGill University, has demonstrated, for the first time, the role that dopamine plays in ...

Apr 03, 2014
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Couch potato? It could be genetic

(Medical Xpress)—Scientists in China and Aberdeen have made a key discovery which could explain why some people are 'couch potatoes'.

Feb 14, 2014
popularity 4 / 5 (4) | comments 0

Is multitasking mastery in the genes?

Human factors/ergonomics researchers have long studied the connection between cognitive function and the ability to perform well on multiple simultaneous tasks, and recently a group of neuroergonomics researchers went a step ...

Jan 07, 2014
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Gel reduced daily tremors in Parkinson's disease

(Medical Xpress)—An experimental treatment for Parkinson's disease reduced by nearly two hours on average the period each day when medication failed to control patients' slowness and shaking, according to results from a ...

Jan 06, 2014
popularity 5 / 5 (1) | comments 0 | with audio podcast

Who learns from the carrot, and who from the stick?

To flexibly deal with our ever-changing world, we need to learn from both the negative and positive consequences of our behaviour. In other words, from punishment and reward. Hanneke den Ouden from the Donders Institute in ...

Nov 22, 2013
popularity 4.2 / 5 (11) | comments 0 | with audio podcast

Dopamine

Dopamine is a neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4, and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary.

Dopamine can be supplied as a medication that acts on the sympathetic nervous system, producing effects such as increased heart rate and blood pressure. However, because dopamine cannot cross the blood-brain barrier, dopamine given as a drug does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson's disease and dopa-responsive dystonia, L-DOPA (levodopa), which is the precursor of dopamine, can be given because it can cross the blood-brain barrier.

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