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Restless legs syndrome, insomnia and brain chemistry: A tangled mystery solved?

Johns Hopkins researchers believe they may have discovered an explanation for the sleepless nights associated with restless legs syndrome (RLS), a symptom that persists even when the disruptive, overwhelming nocturnal urge ...

Neuroscience created May 07, 2013 | popularity 4.4 / 5 (5) | comments 1 | with audio podcast

Maternal diet sets up junk food addiction in babies, study finds

(Medical Xpress)—Research from the University of Adelaide suggests that mothers who eat junk food while pregnant have already programmed their babies to be addicted to a high fat, high sugar diet by the time they are weaned.

Health created Apr 30, 2013 | popularity not rated yet | comments 0 | with audio podcast

Dopamine regulates the motivation to act

The widespread belief that dopamine regulates pleasure could go down in history with the latest research results on the role of this neurotransmitter. Researchers have proved that it regulates motivation, causing individuals ...

Neuroscience created Apr 29, 2013 | popularity 5 / 5 (3) | comments 2

New research examines connection between inflammatory stimulus and Parkinson's disease

Parkinson's disease (PD) is a progressive degenerative disease affecting a person's ability to coordinate and control their muscle movement. What starts out as a tremor in a finger will eventually lead to difficulty in writing ...

Parkinson's & Movement disorders created Apr 23, 2013 | popularity 5 / 5 (1) | comments 0

A noninvasive avenue for Parkinson's disease gene therapy

Researchers at Northeastern University in Boston have developed a gene therapy approach that may one day stop Parkinson's disease (PD) in it tracks, preventing disease progression and reversing its symptoms. The novelty of ...

Parkinson's & Movement disorders created Apr 21, 2013 | popularity not rated yet | comments 0

Taste of beer, without effect from alcohol, triggers dopamine release in the brain

The taste of beer, without any effect from alcohol itself, can trigger dopamine release in the brain, which is associated with drinking and other drugs of abuse, according to Indiana University School of Medicine ...

Neuroscience created Apr 15, 2013 | popularity 5 / 5 (2) | comments 5 | with audio podcast

Breaking down the Parkinson's pathway: How affected brain cells respond during different behavioral tasks

The key hallmark of Parkinson's disease is a slowdown of movement caused by a cutoff in the supply of dopamine to the brain region responsible for coordinating movement. While scientists have understood this ...

Neuroscience created Mar 13, 2013 | popularity 4 / 5 (2) | comments 1 | with audio podcast

New effort to identify Parkinson's biomarkers

Last month, the National Institutes of Health announced a new collaborative initiative that aims to accelerate the search for biomarkers—changes in the body that can be used to predict, diagnose or monitor a disease—in ...

Parkinson's & Movement disorders created Mar 05, 2013 | popularity 5 / 5 (1) | comments 0

Drugs may help relieve restless legs syndrome

(HealthDay)—People suffering from restless legs syndrome may find some relief by taking one of several drugs approved to treat the condition, a new review confirms.

Diseases, Conditions, Syndromes created Mar 04, 2013 | popularity not rated yet | comments 0

Group Therapy: New approach to psychosis treatment could target multiple nervous system receptors

Antipsychotic drugs, used in the treatment of psychotic disorders involving severe delusions and hallucinations, have been studied for more than 70 years. Currently available antipsychotic drugs, however, only alleviate certain ...

Psychology & Psychiatry created Feb 01, 2013 | popularity not rated yet | comments 1

Study reveals promising new target for Parkinson's disease therapies

With a new insight into a model of Parkinson's disease, researchers from the University of Pennsylvania School of Veterinary Medicine have identified a novel target for mitigating some of the disease's toll on the brain.

Parkinson's & Movement disorders created Jan 19, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Mouse research links adolescent stress and severe adult mental illness

Working with mice, Johns Hopkins researchers have established a link between elevated levels of a stress hormone in adolescence—a critical time for brain development—and genetic changes that, in young adulthood, cause ...

Neuroscience created Jan 17, 2013 | popularity 5 / 5 (5) | comments 3 | with audio podcast

Parkinson's treatment can trigger creativity

Parkinson's experts across the world have been reporting a remarkable phenomenon—many patients treated with drugs to increase the activity of dopamine in the brain as a therapy for motor symptoms such as ...

Parkinson's & Movement disorders created Jan 14, 2013 | popularity 4.3 / 5 (4) | comments 1 | with audio podcast

Dopamine-receptor gene variant linked to human longevity

(Medical Xpress)—A variant of a gene associated with active personality traits in humans seems to also be involved with living a longer life, UC Irvine and other researchers have found.

Neuroscience created Jan 03, 2013 | popularity 3.7 / 5 (3) | comments 0 | with audio podcast

Many causes for learning lags in tumor disorder

(Medical Xpress)—The causes of learning problems associated with an inherited brain tumor disorder are much more complex than scientists had anticipated, researchers at Washington University School of Medicine ...

Neuroscience created Dec 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Dopamine

Dopamine is a neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4, and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary.

Dopamine can be supplied as a medication that acts on the sympathetic nervous system, producing effects such as increased heart rate and blood pressure. However, because dopamine cannot cross the blood-brain barrier, dopamine given as a drug does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson's disease and dopa-responsive dystonia, L-DOPA (levodopa), which is the precursor of dopamine, can be given because it can cross the blood-brain barrier.

For more information about Dopamine, read the full article at Wikipedia.
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