News tagged with dopamine

Related topics: brain · parkinson s disease · brain cells · attention deficit hyperactivity disorder · biological psychiatry

Researchers create 'Wikipedia' for neurons

The decades worth of data that has been collected about the billions of neurons in the brain is astounding. To help scientists make sense of this "brain big data," researchers at Carnegie Mellon University have used data ...

Mar 30, 2015
popularity66 comments 0

Dopamine leaves its mark in brain scans

Researchers use functional magnetic resonance imaging (fMRI) to identify which areas of the brain are active during specific tasks. The method reveals areas of the brain, in which energy use and hence oxygen content of the ...

Nov 21, 2014
popularity0 comments 0

Your genes affect your betting behavior

Investors and gamblers take note: your betting decisions and strategy are determined, in part, by your genes. University of California, Berkeley, and University of Illinois at Urbana-Champaign (UIUC) researchers have shown ...

Jun 16, 2014
popularity0 comments 0

GDNF not needed by the midbrain dopamine system

A key factor in the motor symptoms associated with Parkinson's disease is the gradual destruction of dopamine neurons. The glial cell-derived neurotrophic factor, or GDNF, has been proven to protect dopamine neurons in test ...

Mar 04, 2015
popularity10 comments 0


Dopamine is a neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4, and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary.

Dopamine can be supplied as a medication that acts on the sympathetic nervous system, producing effects such as increased heart rate and blood pressure. However, because dopamine cannot cross the blood-brain barrier, dopamine given as a drug does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson's disease and dopa-responsive dystonia, L-DOPA (levodopa), which is the precursor of dopamine, can be given because it can cross the blood-brain barrier.

This text uses material from Wikipedia, licensed under CC BY-SA

Subscribe to rss feed