Social interactions are regulated by the neuronal circuits underlying motivated behaviors. These reward circuits involve the brain's ventral tegmental area and its dopaminergic neurons. However, which brain areas convey information ...
Mar 31, 2022
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Parkinson's disease is a neurodegenerative disorder characterized by the destruction of a specific population of neurons: the dopaminergic neurons. The degeneration of these neurons prevents the transmission of signals controlling ...
Mar 17, 2022
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Parkinson's is a neurodegenerative disease where dopaminergic neurons progressively die in the brainstem. Tremor and difficulties walking are recognizable movement symptoms for many people suffering from Parkinson's. Over ...
Feb 18, 2022
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Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.
Dec 13, 2021
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Human beings, like most mammals, need social interactions to live and develop. The processes that drive them toward each other require decision making whose brain machinery is largely misunderstood. To decipher this phenomenon, ...
Dec 2, 2021
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The neurotransmitter dopamine (DA) has several important functions. For instance, it known to play a role in how we feel pleasure, as well as in our ability to concentrate on everyday task, maintain focus, and learn specific ...
The neurotransmitter dopamine influences the activity of a wide variety of brain areas. A deficiency of this substance can have drastic consequences: The death of dopamine-producing nerve cells in the substantia nigra—a ...
Sep 14, 2021
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Researchers from IDIBELL and the University of Barcelona (UB) report that neurons derived from Parkinson's patients show impairments in their transmission before neurodegeneration. The study used dopaminergic neurons differentiated ...
Jul 7, 2021
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Since 2008, we have known that the 16p11.2 chromosomal region is linked with autism spectrum disorder (ASD). Now, researchers from Boston Children's have developed a new way to study the effects of 16p11.2 deletion in human ...
Jun 9, 2021
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Northwestern Medicine scientists have identified the consequences of contact between the mitochondria and the lysosome in the axons and synapses of human neurons, according to a study published in Nature Communications.
Apr 19, 2021
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