Kinase test may yield big gains for drug-resistant cancers
In a paper published today in the journal Cell, a team from the University of North Carolina at Chapel Hill unveils the first broad-based test for activation of protein kinases "en masse", enabling measur ...
Cancer
Apr 12, 2012 |
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Harmless human virus may be able to boost the effects of chemotherapy
A naturally-occurring harmless human virus may be able to boost the effects of two standard chemotherapy drugs in some cancer patients, according to early stage trial data published in Clinical Cancer Research.
Cancer
Apr 03, 2012 |
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Combination drug treatment can cut malaria by 30 percent
Malaria infections among infants can be cut by up to 30 per cent when antimalarial drugs are given intermittently over a 12 month period, a three-year clinical trial in Papua New Guinea has shown.
Diseases, Conditions, Syndromes
Apr 02, 2012 |
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Two drugs already on the market show promise against tuberculosis
A two-drug combination is one of the most promising advances in decades for the treatment of tuberculosis (TB) — a disease that kills 2 million people annually — a scientist reported today at the 243 National Meeting ...
Medications
Mar 26, 2012 |
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Scientists link two cancer-promoting pathways in esophageal cancer
Identification of a non-traditional pathway for spiriting a cancer-promoting protein into the cell nucleus points to a possible combination therapy for esophageal cancer and indicates a mechanism of resistance for new drugs ...
Cancer
Mar 19, 2012 |
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Trial for new drug-resistant TB treatment to begin
A global health alliance Monday unveiled plans for the first clinical tests of a new treatment regimen for tuberculosis, including for patients with resistance to existing multidrug programs.
Diseases, Conditions, Syndromes
Mar 19, 2012 |
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Study reports steady increases in long-term survival among children with acute lymphoblastic leukemia
A study by the Children's Oncology Group (COG) reported that five-year survival for acute lymphoblastic leukemia (ALL, the most common type of pediatric cancer) among children treated through COG clinical trials increased ...
Cancer
Mar 12, 2012 |
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Blocking telomerase kills cancer cells but provokes resistance, progression
Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...
Cancer
Feb 21, 2012 |
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Combined asthma medication therapy shown to reduce attacks
A Henry Ford Hospital study has found that using two types of common asthma medications in combination reduces severe asthma attacks.
Diseases, Conditions, Syndromes
Feb 06, 2012 |
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Ganetespib showed activity in KRAS-mutant NSCLC as monotherapy and in combinations
The investigational drug ganetespib, a synthetic second-generation Hsp90 inhibitor, slowed the growth of cancer cells taken from non-small cell lung cancer tumors with a mutation in the KRAS gene. The drug was even more active ...
Cancer
Jan 11, 2012 |
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Study finds superior drug combo for difficult-to-control epilepsy
A combination of two common drugs, lamotrigine and valproate, is more effective in treating difficult-to control epilepsy than other anti-epileptic regimens, according to a University of Washington report to be published ...
Neuroscience
Dec 14, 2011 |
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Drug combination highly effective for newly diagnosed myeloma patients, study finds
(Medical Xpress) -- A three-drug combination treatment for the blood cancer multiple myeloma compares favorably to the best established therapy for newly diagnosed patients, according to a multi-center study led by Andrzej ...
Cancer
Dec 08, 2011 |
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NIH discontinues tenofovir vaginal gel in 'VOICE' HIV prevention study
A large-scale clinical trial evaluating whether daily use of an antiretroviral-containing oral tablet or vaginal gel can prevent HIV infection in women is being modified because an interim review found that the gel, an investigational ...
HIV & AIDS
Nov 28, 2011 |
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FDA backs Vytorin for kidney disease patients
(AP) -- The Food and Drug Administration says Merck's cholesterol drug Vytorin helps reduce heart attack, stroke and related problems in patients with kidney disease, a potential new use for the blockbuster drug.
Medications
Oct 31, 2011 |
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TARDIS trial seeks new dimension in stroke treatment
People who suffer from acute stroke or Transient Ischaemic Attack (TIA, a mini stroke) could get better treatment in the future thanks to the expansion of a large clinical trial of a new combination of drugs led by researchers ...
Cardiology
Oct 17, 2011 |
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