Comparing antimalarial drugs and their effects over the Plasmodium lifecycle
In this week's PLoS Medicine, Michael Delves of Imperial College London, UK and colleagues compare the activity of 50 current and experimental antimalarials against liver, sexual blood, and mosquito stages of selected human ...
Diseases, Conditions, Syndromes
Feb 21, 2012 |
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Tuberculosis researchers find answer to 30-year-old puzzle
(Medical Xpress) -- After three decades of searching, the random screening of a group of compounds against the bacterium that causes tuberculosis has led scientists to a eureka discovery that breaks through the fortress that ...
Diseases, Conditions, Syndromes
Feb 21, 2012 |
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New class of potential drugs inhibits inflammation in brain
Scientists at Emory University School of Medicine have identified a new group of compounds that may protect brain cells from inflammation linked to seizures and neurodegenerative diseases.
Neuroscience
Feb 14, 2012 |
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US issues guidelines to avoid heparin contamination
Four years after US drug-maker Baxter International's blood thinner heparin was contaminated in China, causing dozens of deaths, US regulators on Friday issued draft guidelines for safe production.
Medications
Feb 10, 2012 |
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Study: Rapid bone loss as possible side effect of anti-obesity drug now in clinical trials
An endocrine hormone used in clinical trials as an anti-obesity and anti-diabetes drug causes significant and rapid bone loss in mice, raising concerns about its safe use, UT Southwestern Medical Center researchers ...
Medical research
Feb 07, 2012 |
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New drug extends survival in patients with drug-resistant prostate cancer
A new drug, MDV3100, is improving the survival rate in men with advanced prostate cancer, results of a large, phase III clinical trial show. The drug is designed to block a type of cellular receptor that drives progression ...
Cancer
Feb 01, 2012 |
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Researchers study how chemicals in drugs and around us impact stem cells
Chemicals in pharmaceutical drugs can obviously save lives. But as more and stronger chemicals have been introduced, our basic knowledge of the broader health impact of all these chemicals has not kept up with the rapid pace ...
Medical research
Jan 17, 2012 |
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Zebrafish may help speed drug discovery
Tiny zebrafish just may give scientists one solution to information overload in the search for new drugs therapies.
Medical research
Jan 17, 2012 |
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New antibiotic compound enters phase I clinical trial
(Medical Xpress) -- Novacta Biosystems has commenced dosing of the first healthy volunteers in a phase I clinical trial of a new antibiotic to treat the hospital superbug Clostridium difficile.
Medications
Nov 09, 2011 |
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Researchers develop new way to screen for brain cancer stem cell killers
Researchers with UCLA's Jonsson Comprehensive Cancer Center have developed and used a high-throughput molecular screening approach that identifies and characterizes chemical compounds that can target the stem cells that are ...
Cancer
Oct 11, 2011 |
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New drug could combat killer diseases
(Medical Xpress) -- Researchers from the University of Reading have developed a new drug which could reduce the spread of deadly diseases such as Lassa Fever and Aseptic Meningitis.
Medical research
Sep 30, 2011 |
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Researchers develop drug-like molecules to improve schizophrenia treatment
Researchers at Vanderbilt University have identified chemical compounds that could lead to a major advance in the treatment of schizophrenia.
Medical research
Sep 22, 2011 |
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Scientists uncover new ways to stimulate pancreatic beta cell growth
One of the holy grails in diabetes research is to discover molecules that stimulate beta cell growth and to find drugs that target these molecules. Now, JDRF-funded researchers in collaboration with the pharmaceutical company ...
Medical research
Sep 06, 2011 |
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Structural Genomics Project creates blueprint for infectious disease and biodefense research
The September issue of the online scientific journal Acta Crystallographica: Structural Biology and Crystallization Communications (Acta Cryst F) will consist entirely of work done at the Seattle Structural Genomics Center ...
Diseases, Conditions, Syndromes
Sep 01, 2011 |
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MIABE standard opens up new opportunities in drug discovery
An international consortium of pharmaceutical companies, public and commercial data providers and academic groups has agreed on a new standard for describing the effect of a compound on a biological entity. Published in Nature Re ...
Other
Aug 31, 2011 |
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