Researchers at Johns Hopkins Bloomberg School of Public Health have demonstrated the use of stem-cell-derived "mini-brains" to detect harmful side effects of a common drug on the developing brain. Mini-brains are miniature ...
Feb 21, 2020
0
604
The U.S. Food and Drug Administration (FDA) approves only 13.8% of all tested drugs, and these numbers are even lower in "orphan" diseases that affect relatively few people.
Jan 27, 2020
0
97
Drug development is an extremely arduous and costly process, and failure rates in clinical trials that test new drugs for their safety and efficacy in humans remain very high. According to current estimates, only 13.8% of ...
Jan 27, 2020
0
251
Bumetanide—a prescription drug for oedema (the build-up of fluid in the body) - improves some of the symptoms in young children with autism spectrum disorders and has no significant side effects, according to a new study ...
Jan 27, 2020
0
314
Senescent cells, which stop dividing under stress, are long- recognized drivers of multiple diseases of aging. Mouse studies have shown that targeted removal of these cells and the inflammatory factors they secrete, known ...
Jan 16, 2020
0
345
Brain imaging of pathological tau-protein "tangles" reliably predicts the location of future brain atrophy in Alzheimer's patients a year or more in advance, according to a new study by scientists at the UC San Francisco ...
Jan 2, 2020
0
789
Immunologists at St. Jude Children's Research Hospital have discovered key biological switches that control regulatory T cells—specialized white blood cells that keep the immune system in check. A paper detailing this work ...
Oct 24, 2019
0
320
A new approach to treat advanced breast cancer shuts down the growth of cells that become resistant to standard hormone therapy, according to Duke Cancer Institute animal studies.
Oct 23, 2019
0
172
Northwestern Medicine scientists have used patient-derived neurons to develop and test a new strategy to treat Parkinson's disease by mitigating the effects of harmful genetic mutations, as detailed in a study published today ...
Oct 17, 2019
0
369
Some of the genes that predict the risk of high cholesterol don't apply to people from Uganda the same as they do in European populations, finds a new UCL-led study.
Sep 24, 2019
1
101
