Medications

Managing pain in the age of opioids

The data supporting the use of opioids to treat chronic, non-cancer pain is quite weak, says Michael Ashburn, director of the Penn Pain Medicine Center at the Perelman School of Medicine. As few as one in five patients may ...

Medical research

Loose RNA molecules rejuvenate skin, researchers discover

Want to smooth out your wrinkles, erase scars and sunspots, and look years younger? Millions of Americans a year turn to lasers and prescription drugs to rejuvenate their skin, but exactly how that rejuvenation works has ...

Medications

Drug overdose epidemic has been growing exponentially for decades

Death rates from drug overdoses in the U.S. have been on an exponential growth curve that began at least 15 years before the mid-1990s surge in opioid prescribing, suggesting that overdose death rates may continue along this ...

Medications

Study: Side effects emerge after approval for many US drugs

Almost one-third of new drugs approved by U.S. regulators over a decade ended up years later with warnings about unexpected, sometimes life-threatening side effects or complications, a new analysis found.

Cardiology

What's behind the heartbreaking risk of anti-inflammatory drugs

Researchers have known for more than a decade that the risk of heart disease and stroke increases when people take pain relievers like ibuprofen and other non-steroidal anti-inflammatory drugs, or NSAIDs. Now, scientists ...

Psychology & Psychiatry

Harder-to-abuse OxyContin doesn't stop illicit use

A reformulation of OxyContin that makes it harder to abuse has curtailed the drug's illicit use. But some 25 percent of drug abusers entering rehab said they still abused the prescription painkiller despite package labeling ...

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