The cancer gene MYC has been called the "Mount Everest" of cancer research because of the difficulty of designing medications that can disable it and the expectation that an effective MYC drug could help so many cancer patients. ...
May 24, 2023
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Mitochondria, tiny structures within each cell that regulate metabolism and energy use, may be a promising new target for cancer therapy, according to a new study. Manipulation of two biochemical signals that regulate the ...
Feb 21, 2012
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Researchers from the Walter and Eliza Hall Institute have for the first time identified a 'programmed cell death' pathway in parasitic worms that could one day lead to new treatments for one of the world's most serious and ...
Sep 28, 2011
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(Medical Xpress)—A team of researchers with member affiliations to institutions in the U.S. and Hong Kong, has found that researchers going after drug targets that have supporting genetic evidence could double the success ...
Blocking the uptake of large amounts of cholesterol into brain cancer cells could provide a new strategy to battle glioblastoma, one of the most deadly malignancies, researchers at UCLA's Jonsson Comprehensive Cancer Center ...
Sep 15, 2011
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Researchers report that a drug targeting the cancer-causing gene MYC inhibits the function of the gene in a phase I clinical trial. Until now, no other drug has been able to do this safely and effectively.
Oct 26, 2022
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Scientists have created a map of all 1,578 licensed drugs and their mechanisms of action - as a means of identifying 'uncharted waters' in the search for future treatments.
Dec 5, 2016
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(Medical Xpress)—A University of Alberta researcher has pinpointed a mutation that brings the medical community another step closer to treating those who suffer from a fatal type of muscular dystrophy.
Jul 30, 2013
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A novel screening method developed by a team at Dana-Farber/Boston Children's Cancer and Blood Disorders Center—using CRISPR-Cas9 genome editing technology to test the function of thousands of tumor genes in mice—has ...
Jul 19, 2017
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The HIV-1 virus can neutralize cellular defenses with its viral infectivity factor (Vif). OIST researchers Prof. Matthias Wolf and Dr. Takahide Kouno together with an international team of colleagues have now determined the ...
Jul 14, 2023
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