Inheriting a normal and intact number of chromosomes in germ cells, egg and sperm, is essential for the preservation of all species. With increasing age, the risk of the egg cell not inheriting the normal set of chromosomes ...
Feb 4, 2022
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Glioblastoma is the most lethal and malignant adult brain cancer that may arise from neuroglial stem or progenitor cells. Certain gene mutations or those with a known history of other cancers and radiation therapy may predispose ...
Sep 15, 2021
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Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells. Moreover, they were able to apply their findings ...
Sep 14, 2021
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A team of researchers affiliated with a host of institutions across Japan has created, for the first time, viable mice eggs from scratch using stem cells. In their paper published in the journal Science, the group describes ...
For the first time, researchers have shown how Mullerian inhibiting substance (MIS), also known as anti-Mullerian hormone, a key reproductive hormone, suppresses follicle development and prevents ovulation in females. "Understanding ...
May 3, 2021
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An epigenetic study at the RIKEN Center for Integrative Medical Sciences shows that in mouse egg cells, modifications to histone H2A at lysine 119 lay the groundwork for inherited DNA functional modifications from the mother.
Apr 7, 2021
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Genetic mutations which occur naturally during the earliest stages of an embryo's development can cause the severe birth defect spina bifida, finds a new experimental study in mice led by UCL scientists.
Feb 19, 2021
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Recently published work from Carnegie's Allan Spradling and Wanbao Niu revealed in unprecedented detail the genetic instructions immature egg cells go through step by step as they mature into functionality. Their findings ...
Oct 8, 2020
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Increasing the levels of a chemical found in all human cells could boost a woman's fertility and help select the best eggs for IVF, according to University of Queensland research.
Jul 7, 2020
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Scientists have created a mathematical model that can help explain why so many pregnancies and in vitro fertilization attempts fail.
Apr 13, 2020
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