Anaplastic large cell lymphoma, a form of non-Hodgkin lymphoma, is the most common aggressive lymphoma in children. Chemotherapy and radiation fail to cure about 30% of cases. When tumors are driven by the oncogene ALK—which ...
Aug 3, 2023
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Blood vessels keep us alive. They are the highways that transport oxygen-rich blood and nutrients to all corners of our body—feeding our tissue and organs—while simultaneously removing toxic waste products.
Aug 1, 2023
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Scientists at UT Southwestern Medical Center and Children's Medical Center Dallas have discovered in mice how high cholesterol causes blood vessels to become inflamed, a necessary prerequisite for atherosclerosis—the "hardening ...
Jul 25, 2023
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What makes the vital layer of protective cells around the brain and spinal cord—the blood-brain barrier—more or less permeable has been one of the more mystifying questions in neuroscience.
Jul 13, 2023
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Therapeutic antibodies that cause aggressive tumors to become susceptible to treatment are being studied with the hope of one day changing the fate of patients who either relapse soon after cancer therapy or whose stubborn ...
Northwestern Medicine investigators have discovered a novel mechanism that regulates neutrophil recruitment into tissue during inflammation, which could be targeted to treat different inflammatory diseases and conditions, ...
Jun 30, 2023
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A new study published in Nature Cardiovascular Research uncovers the crucial role of the AmotL2 protein in connecting mechanical forces to endothelial cell integrity and alignment. This discovery sheds light on junctional ...
Jun 30, 2023
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Most people know that the risk factors for heart disease are high blood pressure, smoking, raised cholesterol and being overweight. However, many people who have a heart attack do not have any of these traditional risk factors.
Jun 16, 2023
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Multiple myeloma is an incurable bone marrow cancer that kills over 100,000 people every year. Known for its quick and deadly spread, this disease is one of the most challenging to address. As these cancer cells move through ...
Jun 15, 2023
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A study led by Daniel Jane-Wit, MD, Ph.D., a Yale School of Medicine associate professor of medicine (cardiology) and of immunobiology, could revolutionize our understanding of immune signaling. The study, published May 24 ...
Jun 14, 2023
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