Diseases, Conditions, Syndromes

How a SARS-CoV-2 infection can become severe COVID-19

Infection with SARS-CoV-2 leaves some people almost unaffected, while others develop life-threatening COVID-19 symptoms. So far, we do not understand exactly why symptoms and disease severity, especially in infections with ...

Cardiology

New advice on arthritis drugs

New research evaluating the drugs commonly used by rheumatoid arthritis patients suggests two combinations could reduce the risk of heart attack and strokes.

Medical research

The biomechanics of vascular aging

Cardiovascular diseases (CVD) lead to atherosclerosis and heart failure and are prevalent age-related illnesses in humans. In a new study, published in the renowned journal JCI, scientists from Roland Foisner's group at the ...

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Endothelium

The endothelium is the thin layer of cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall. These cells are called endothelial cells. Endothelial cells line the entire circulatory system, from the heart to the smallest capillary. These cells reduce turbulence of the flow of blood, allowing the fluid to be pumped farther.

Endothelial tissue is an epithelial tissue.

The endothelium normally provides a non-thrombogenic surface because it contains heparan sulfate which acts as a cofactor for activating antithrombin III, a protease that inactivates several factors in the coagulation cascade.

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