News tagged with epigenetic changes
Related topics: dna sequences , dna methylation , genome , gene activity , cancer cells
Genetic predictors of postpartum depression uncovered
Johns Hopkins researchers say they have discovered specific chemical alterations in two genes that, when present during pregnancy, reliably predict whether a woman will develop postpartum depression.
Psychology & Psychiatry
22 hours ago |
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Shedding light on the long shadow of childhood adversity
Childhood adversity can lead to chronic physical and mental disability in adult life and have an effect on the next generation, underscoring the importance of research, practice and policy in addressing this issue, according ...
Psychology & Psychiatry
Apr 30, 2013 |
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Can caesarean sections increase susceptibility to disease?
Despite efforts to reduce intervention rates during labour, vaginal births without medical intervention are becoming increasingly rare in Australia and overseas: nearly one in three women in Australian now ...
Health
Apr 24, 2013 |
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Epigenetic changes shed light on biological mechanism of autism
Scientists from King's College London have identified patterns of epigenetic changes involved in autism spectrum disorder (ASD) by studying genetically identical twins who differ in autism traits. The study, published in ...
Autism spectrum disorders
Apr 23, 2013 |
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The relationship between prenatal stress and obesity is confirmed in rats
The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated ...
Health
Apr 09, 2013 |
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KDM1 may represent a new therapeutic target for glioma
Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to Gangadhara R. Sareddy, Ph.D., a postdoctoral ...
Cancer
Apr 08, 2013 |
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Reversing blood and freshening it up
The blood of young and old people differs. In an article published recently in the scientific journal Blood, a research group at Lund University in Sweden explain how they have succeeded in rejuvenating the blood of mice b ...
Medical research
Mar 25, 2013 |
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Researchers link cancer to failures in chromosome protection for the first time
A study published today in the journal Nature Genetics explores a new mechanism that may contribute to the development of several tumours, including Chronic Lymphocytic Leukaemia, a type of cancer that affects more than a ...
Genetics
Mar 19, 2013 |
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New clues in hunt for heredity in type 2 diabetes
Type 2 diabetes has strong hereditary tendencies and the genes we are born with cannot be changed. However, new research from Lund University in Sweden shows that we can modify the function of the genes through the epigenetic ...
Genetics
Mar 19, 2013 |
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Epigenetic changes play a key role in development of chemo resistance in BCa
At the 28th Annual EAU Congress currently ongoing in Milan until Tuesday, W. Tan and colleagues presented their study on neoadjuvant cisplatin-based chemotherapy which showed that epigenetic changes are potential key drivers ...
Cancer
Mar 18, 2013 |
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Colon cancer exhibits a corresponding epigenetic pattern in mice and humans
Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between ...
Genetics
Feb 07, 2013 |
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Personal epigenetic 'signatures' found consistent in prostate cancer patients' metastases
In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient. The discovery of the ...
Cancer
Jan 23, 2013 |
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Search for epigenetic decoder leads scientists to Rett Syndrome
(Medical Xpress)—A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at the time, but a ...
Medical research
Dec 21, 2012 |
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New evidence for epigenetic effects of diet on healthy aging
New research in human volunteers has shown that molecular changes to our genes, known as epigenetic marks, are driven mainly by ageing but are also affected by what we eat.
Genetics
Dec 06, 2012 |
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Biomarkers of behavior, therapeutic targets for adult B-acute lymphoblastic leukemia identified
New insight into the aggressive behavior of certain adult B-acute lymphoblastic leukemias has provided researchers with a potential new prognostic biomarker and a promising new therapeutic target.
Cancer
Oct 29, 2012 |
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