EpiPens still costly despite generic alternatives, other reforms
If Meg White ever got stung by a bee, her EpiPen could ultimately save her life.
Feb 12, 2020
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If Meg White ever got stung by a bee, her EpiPen could ultimately save her life.
Feb 12, 2020
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US regulators Thursday approved the first generic alternative for the EpiPen, a life-saving emergency allergy medicine, two years after soaring prices for the original version owned by Mylan stoked controversy.
Aug 16, 2018
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As a young adult, Javier Evelyn didn't always carry his epinephrine autoinjector, which dispenses the medicine he needs if he has a food allergy reaction. It wasn't cool to carry a clunky piece of equipment, he recalled.
Oct 27, 2021
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Cancer: The word alone evokes dread, anxiety, and fear. Accordingly, many women living with the disease and undergoing treatment experience chronic stress and depression. Scientists have demonstrated, in studies with rodents ...
Feb 19, 2019
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Outside advisors for the U.S. Food and Drug Administration voted Thursday to recommend approval of Neffy, the first epinephrine nasal spray for severe allergic reactions.
May 12, 2023
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If you are one of the millions of Americans who experiences a severe allergic reaction to food, latex or an insect sting, you should know the first line of defense in combating the reaction is epinephrine. Unfortunately, ...
Dec 2, 2014
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McMaster researchers will be following a pilot project being launched in Hamilton's Jackson Square shopping mall to make epinephrine auto-injectors (EAIs) available to the public.
Sep 10, 2014
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(HealthDay)—Asthma or allergies can put a damper on holiday gatherings. But there are ways you can stay healthy, the American College of Allergy, Asthma and Immunology says.
Nov 28, 2019
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Treatment guidelines for managing anaphylaxis in children should be reassessed, according to a new Canadian study published in the Journal of Allergy and Clinical Immunology: In Practice.
May 31, 2019
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Epinephrine autoinjectors can be life-saving for patients experiencing anaphylaxis - a life-threatening emergency - but a new case series published online Tuesday in Annals of Emergency Medicine identifies design features ...
Oct 8, 2015
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Epinephrine (also known as adrenaline) is a hormone and a neurotransmitter. It increases heart rate, constricts blood vessels, dilates air passages and participates in the fight-or-flight response of the sympathetic nervous system. Chemically, adrenaline is a catecholamine, a monoamine produced only by the adrenal glands from the amino acids phenylalanine and tyrosine.
The term adrenaline is derived from the Latin roots ad- and renes and literally means "on the kidney", in reference to the adrenal gland's anatomic location on the kidney. The Greek roots epi means on top of, while "Nephros" refers to the kidneys. These roots combined create adrenaline which roughly translates to "pertaining to on top of the kidneys" which is also the anatomical location of the adrenal glands. The term epinephrine is often shortened to epi in medical jargon.
Epinephrine is released during sexual arousal and it plays a very important role in orgasm. It has also the function to maintain the heart beat rate to keep the sexual arousal. It is produced by the adrenal glands and it is used during extensive exercise and maintaining bodily functions. Other functions and secretions are discussed in the article.
Adrenal extracts containing adrenaline were first obtained by Polish physiologist Napoleon Cybulski in 1895. These extracts, which he called nadnerczyna, contained adrenaline and other catecholamines. Japanese chemist Jokichi Takamine and his assistant Keizo Uenaka independently discovered adrenaline in 1900. In 1901, Takamine successfully isolated and purified the hormone from the adrenal glands of sheep and oxen. Adrenaline was first synthesized in the laboratory by Friedrich Stolz and Henry Drysdale Dakin, independently, in 1904.
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