Medical research

Discovery of a protein controlling resistance to chemotherapy

Despite the recent development of new targeted therapies, chemotherapies remain the most frequently used treatment to treat patients suffering from advanced cancers. Chemotherapy resistance is one of the main causes of treatment ...

Immunology

Molecular component of caffeine may play a role in gut health

Brigham researchers studying how and why certain cell types proliferate in the gut found that xanthine, which is found in coffee, tea and chocolate, may play a role in Th17 differentiation. Insights may help investigators ...

Immunology

Immune cells hold clues to vitamin D absorption, study suggests

Vitamin D plays an integral role in regulating immune function, and Penn State researchers have identified immune cells in mice that can be differentiated by whether or not they have vitamin D receptors—a finding that could ...

Medical research

Exploring how fungal spores hijack lung cells

The pathogenic fungus Aspergillus fumigatus escapes elimination from surface cells of the human lung by binding to a human protein. In doing so, it is able to nest in so called phagosomes, confined areas in the lung cells, ...

Health

DNA damage levels similar in vapers and smokers, study finds

E-cigarettes—used regularly by more than 10% of U.S. teens and more than 3% of adults—were once pitched as a healthy alternative to tobacco cigarettes. But research increasingly links the use of e-cigarettes, or vaping, ...

Immunology

Researchers reveal metabolic processes key to lung repair

Scientists at the Francis Crick Institute have uncovered how cells lining the lung airways change their metabolism, and how this process is key to helping the lungs heal after infection or damage.

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