Medical research

Alterations to gut mucus may trigger ulcerative colitis

Ulcerative colitis is the most common type of inflammatory bowel disease, characterized by chronic ulcers and inflammation in the colon and rectum. Symptoms can be lifelong and range from mild to life-threatening. There is ...

Medical research

Stopping the spread: Targeting tumor metastasis

The process of metastasis is when cancer cells gain motility and spread to other sites of the body. Because this is one of the main causes of cancer-related deaths, researchers have aimed to develop therapeutic strategies ...

Immunology

Study identifies key player in T cell 'education'

Vanderbilt researchers have identified a protein that is key to the "education" of immature T cells in the thymus. The findings, reported in the Journal of Experimental Medicine, could inform therapeutic strategies for enhancing ...

Immunology

Keeping balance inside and outside the small intestine

In the normal small intestine, the levels of SFB and Th17 cells are both maintained as they counterbalance each other. Th17 cells release IL-17 to limit unwanted expansion of SFB, whereas a decrease in the number of SFB eases ...

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